Sentences with phrase «growing vaccine virus»

Kieny said that for reasons that aren't fully understood, vaccine companies that use eggs to grow vaccine viruses get yields of only 25 % to 50 % of those obtained during the production of seasonal vaccine.

Not exact matches

Joy: Yeah, but the point is we have the technology now to sequence and manufacture vaccines fairly quickly; and ideally they wouldn't be grown in eggs or whatever, right; because what if it starts as a virus in chickens or something, and we're screwed.
Both vaccines were based on live, weakened strains of polio virus grown in monkeys» kidney cells.
At the centre of the theory is the plausible, if unlikely, speculation that a direct forerunner of HIV contaminated monkey cells that were used to grow polio virus for the vaccines.
The company uses cells to grow the virus for the vaccine and claims that this «shows significant time saving» over traditional production with eggs.
The new sugar molecule hinders the virus's ability to grow in eggs — so once the vaccine strains are put into eggs, they ditch it.
Frieden, who called the delays «enormously frustrating,» said manufacturers have difficulty growing the viruses used to make vaccine.
Despite efforts to immunize more girls against HPV with the Gardasil or Cervarix vaccines — and continued debate about recommending the vaccine for boys — experts expect that number of these virus - linked cancers to continue to grow.
Kirschstein worked on another aspect of vaccine safety, doing «very prominent» early research on another virus, simian virus 40, which contaminated some of the monkey cells used to grow poliovirus for the Salk vaccine, says Singer, who later joined the same field.
The loss was bad for the vaccine: In a series of experiments Hensley and his colleagues showed antibodies from humans and ferrets (a good animal model for influenza A studies) that had been exposed to the egg - grown vaccine did not effectively kill the circulating sugar - adorned viruses.
That's bad news: the more virus a vaccine requires, the fewer doses that can be grown in a given time.
He notes that the new study is especially relevant because it worked in mammalian cells, which ultimately are a better way to grow the virus than eggs: It's a faster production system and avoids mutations that occur when the virus adapts to chicken eggs, which can compromise vaccine effectiveness.
HCV can not be grown reliably in the laboratory, a failing that has slowed critical studies of everything from drugs to vaccines to basic knowledge of the virus's life cycle.
The best strains we have for a H1N1 swine flu vaccine grow only as half as fast as ordinary vaccine viruses, meaning poorer nations may not get it in time if there is a second wave
So, due to natural changes in the virus as it evolves, as well as due to mutations that may be caused by growing the vaccine strain, the circulating virus and the vaccine become less well matched over time.
«We have solved a fundamental problem that scientists had accepted would be part of vaccine production — that the virus is always going to mutate if it is grown in eggs,» said senior study author Nicholas S. Heaton, Ph.D., assistant professor of molecular genetics and microbiology at Duke University School of Medicine.
The RabAvert ® rabies vaccine (Chiron Corporation, Emeryville, California, United States) is a sterile freeze - dried vaccine obtained by growing the fixed - virus strain Flury LEP in primary cultures of chicken fibroblasts.
«It is better to produce influenza viruses for vaccine production in cells instead of eggs, but the problem is that influenza virus does not grow well in cell culture compared with embryonated eggs.»
In human medicine, our growing knowledge about the role of viruses as a cause of certain cancers has led to the development of vaccines as preventives, such as vaccines against human papillomaviruses, the main cause of cervical cancer in women.
Viruses in vaccines are grown on living tissue, and they're often from other species.
This occurs because the viruses and bacteria used in vaccines are grown in cell cultures and nourished with calf serum.
In those later cases, it was often the modified live virus in the vaccine itself that grew and caused the illness.
In human medicine, our growing knowledge about the role of viruses as a cause of certain cancers has led to the development of vaccines as...
The rest of these vaccines are freeze - dried living virus that have been grown in tissue culture in a way that makes them non-pathogenic (weak) i.e. unable to cause disease.
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