Sentences with phrase «grown cells in culture»

«It might be possible to grow these cells in culture then bank them so that if or when the mother develops some disease later in life, such as diabetes, her cells may be defrosted and differentiated into pancreatic beta cells,» says Lyle Armstrong of Newcastle University, UK, although he too, cautions that more tests are needed to determine exactly what these cells are.

Researchers had developed the technologies needed to create organoids years before — how to grow cells in culture, how to isolate stem cells from human tissue, and how to coax the stem cells, undifferentiated and immature, to become specific types of cells at later stages of development.

Not exact matches

The trial was actually supposed to launch back in August but was delayed because growing and culturing the genomically edited cells took longer than originally expected.

Based on a 3D image such as an MRI scan, Aspect's machine builds relatively complex organic structures out of a «hydrogel» embedded within cells taken from the body and grown in a cell culture.

While some still object to cells being taken from animals and used by scientists to grow clean meat in laboratories — and some just don't like the idea of eating a «cultured» steak created by men and women in white coats — others see the lab - grown meat revolution as key to solving the environmental crisis linked to meat eating.

Researchers hope the organoids will be better than lab animals or cells growing in culture at revealing how the human brain develops, both normally and when things go awry, and identify potential therapeutic or genome - editing targets.

The most promising chemical — sulforaphane, a naturally occurring compound found in cruciferous vegetables — tamped down glucose production by liver cells growing in culture, and shifted liver gene expression away from a diseased state in diabetic rats.

The scientists also showed, in lab - cultured human cells, that an ALDH - blocking drug strips regulatory T - cells of their ability to grow and protect themselves from cyclophosphamide.

Using human fetal «mini-brains» grown in 3 - D cultures, scientists determined that a specific protein produced by the Zika virus changes the properties of neural stem cells in the developing brain of an infected fetus, potentially causing microcephaly in newborns (Ki - Jun Yoon, abstract 103.06, see attached summary).

Dr. Zubair already grows such cells in his Mayo Clinic laboratory using a large tissue culture and several incubators — but only at a snail's pace.

One would culture thin sheets of meat, seeded by cells from a living animal, on a reusable polymer scaffold; the other would grow meat on small edible beads that stretch with changes in temperature.

As a graduate student at Princeton University, Moshe Pritsker tried in vain to grow a culture of embryonic stem cells from instructions laid out in the methods section of a journal article.

To find out, they put droplets of culture medium that cancer cells had grown in on one side of petri dishes.

The bacterium produced an antibiotic, dubbed lugdunin, which killed a slew of superbugs in cell cultures and mice with no signs yet of growing resistance.

The team used human embryonic stem cells — which can transform into any cell of the body — and cultured them in a mixture of chemicals to grow human brain cells.

Mackay - Sim's team has solved those problems by developing a method of removing the cells under a local anaesthetic and growing them in culture to produce larger numbers.

The cells are grown in the incubator in different concentrations in a culture medium.

In studies with human fibroblasts that make up connective tissue, Boger's team tested whether NOD1 activity could affect CMV replication in cultures of cells grown in the laIn studies with human fibroblasts that make up connective tissue, Boger's team tested whether NOD1 activity could affect CMV replication in cultures of cells grown in the lain cultures of cells grown in the lain the lab.

Writing in the May 4 online issue of the journal Scientific Reports, researchers at University of California, San Diego School of Medicine used a powerful statistical tool called «design of experiments» or DOE to determine the optimal cell culture formula to grow and produce hPSCs.

This was observed in human ovarian cancer cells grown in culture, and then in mouse models of the disease.

It isn't clear exactly why the differences fade, Hochedlinger says, but it may be that the expression of embryonic genes is strengthened as the cells grow in culture, gradually overwriting the cells» old gene - expression patterns.

A human brain cell culture grown in vitro has spontaneously transformed, as determined by morphology, growth characteristics, and karyotype analysis.

«Signaling pathways and gene expression profiles are very different in cells that grow in 2D and 3D cultures,» says Oksana Sirenko, a research scientist at Molecular Devices in Sunnyvale, California.

Hsiao and colleagues carefully gathered skin samples from donors, and then grew the skin cells in culture before converting them into iPS cells using the methods created by Yamanaka.

After reactivating the cells with an electric shock, the group grew several oocytes in culture to the blastocyst stage.

With the help of my colleagues I started growing retroviral vector - containing plasmids in bacterial cultures, isolating the plasmid DNA and transfecting special producer cell lines with these plasmids.

Part of the trouble is the ingredients: Subtle variations in tissue - culture chemicals and Matrigel, or in different stem cell lines and how they are grown first in 2 - D culture, can have a big impact on how the organoids turn out, Novitch says.

Moving forward, he was able to place these taste stem cells in a culture dish and prompt them to grow into the different mature taste cell types, thus creating a taste bud in a dish — scientifically known as taste organoids.

In cells grown on flat culture dishes, the expression of thousands of genes didn't match up with their normal patterns, explaining why the cells from those dishes had been unable to generate new hair follicles.

Results suggest that cells grown in the device exhibit more natural behaviors than when grown in traditional culturing methods, and the filtration by the glomerulus is necessary for healthy cell function.

So far, VTT has used cells from its own culture collection to grow Arctic bramble cells, cloudberry cells and stone bramble cells in the CellPod.

«Next steps may include efforts to grow these viruses in cell culture and functional analyses to assess their risk of being transmitted to primate hosts.»

«In the last few years, it has become possible to order cultures of human cells for testing, but they're grown on a plate, a two - dimensional environment,» says Radisic.

Printing out cells grown in culture would eliminate these problems.

The microbes rely on oxygen, carbon and other nutrients in their deep environment to live, but Røy's team found that carbon is so limited that the cells respire oxygen 10,000 times slower than bacteria in lab - grown cultures.

The work was led by Dan S. Kaufman, a hematologist, and James A. Thomson, the first scientist to grow human embryonic stem cells in culture.

This ability to isolate, culture and grow the cancer cells will allow researchers to zero in on the cancer cells that matter to the health of the patient.

During an early clinical trial at the Miami Project last year, researchers took Schwann cells from an easily accessible sensory nerve in a patient's leg, grew them in culture and injected them at the point of the spinal cord injury.

In practice, however, lung cells — especially from older, ill patients — won't grow well enough in culture, but will have to be produced from stem cells or induced pluripotent stem (iPS) cells, she sayIn practice, however, lung cells — especially from older, ill patients — won't grow well enough in culture, but will have to be produced from stem cells or induced pluripotent stem (iPS) cells, she sayin culture, but will have to be produced from stem cells or induced pluripotent stem (iPS) cells, she says.

To shock the plants, Cuello applied a 30 to 100 milliamp current to the growth - medium of plants grown hydroponically, or, in the case of barrel medic, to the solution surrounding the cell cultures.

When the researchers used gene engineering techniques to knock out DDX3 expression in laboratory - grown cell cultures that highly expressed this protein, cell proliferation was half that of cell cultures with high DDX3 expression.

In BRIC 17 - 1, cell cultures derived from thale cress plants are grown in Petri dishes and later examined to determine which genes are involved in certain cellular changeIn BRIC 17 - 1, cell cultures derived from thale cress plants are grown in Petri dishes and later examined to determine which genes are involved in certain cellular changein Petri dishes and later examined to determine which genes are involved in certain cellular changein certain cellular changes.

Petri - dish cultures grew into flat cell sheets, while those in a weightless chamber grew into 3 - D spheres.

By functionally linking the signal transduction of melanopsin to the control circuit of the nuclear factor of activated T cells, we have designed a synthetic signaling cascade enabling light - inducible transgene expression in different cell lines grown in culture or bioreactors or implanted into mice.

«The culture conditions needed to grow various kinds of stem cells can be very tricky,» down to the source of the water, says neural stem cell biologist David Anderson of the California Institute of Technology in Pasadena.

Interestingly, the outbreak strain grew at a normal pace in cultured human white blood cells, apparently by subverting the immune response to its benefit.

Studies by Bausch and others have also detected live Ebola virus in sexual fluids that can successfully grow in cell culture, suggesting it could also lead to infections in other individuals.

To find out if the new viruses actually cause disease, researchers can try to grow them in cell culture and infect animals with them.

In the West, these have been replaced by safer, more effective vaccines grown in cell cultureIn the West, these have been replaced by safer, more effective vaccines grown in cell culturein cell cultures.

The researchers, led by University of California, San Diego neuroscientist Mark Tuszynski, took skin cells from the patients, grew them up in a culture dish and genetically engineered them to make human nerve growth factor (NGF).