Many have suggested that embryonic stem cells could cure type 1 diabetes if researchers could transplant lab -
grown islet cells.
Not exact matches
Too little VEGF doesn't
grow vessels rapidly enough to maintain the transplanted
islets, which are clusters containing hundreds of
cells.
Melton's ultimate goal is to discover how embryonic stem
cells grow into special
cells called
islets in the pancreas.
In these two microscopy images, human
islets (the source of insulin
cells) were poisoned with a drug to remove the insulin
cells, and then treated with either an empty virus (left panel) or the therapeutic virus (right panel), and then
grown in a diabetic mouse.
They all sounded three sour notes: that they had cured only about half of their mice; that they did not know whether the mice had
grown new
islets or merely revived dormant ones; and that they had found no evidence that spleen
cells had converted to beta
cells.
Experts say the length of his survival is mainly because he had a slow -
growing, rare cancer called a pancreatic neuroendocrine
islet cell tumor.
But the application describes ViaCyte's technology, which
grows pancreatic «
islet»
cells from human embryonic stem
cells.
Zeng and his team were able to reverse late - stage type 1 diabetes in lab mice through this strategy, not only halting the autoimmune process, but also helping new
islet cells grow.