Sentences with phrase «growth of new blood vessels»

In mice, exercise generally stimulates growth of new blood vessels and boosts muscle mass.

When the team tested the drug on cells grown in the lab, they found that it killed blood vessel cells and prevented growth of new blood vessels.

Therapeutic benefits of HBOT include a greatly increased oxygen concentration in all body tissues (even with reduced blood flow), improved healing time of stubborn wounds, stimulated growth of new blood vessels in areas of reduced circulation.

At the institute, gene discovery is the province of Julia Ljubimova, a molecular biologist who has isolated laminum - 8, a gene she believes is responsible for the rapid growth of new blood vessels in the most invasive cancers.

In another study of mice injected with GDF11, postdoc Lida Katsimpardi and others in the lab of Harvard neuroscientist Lee Rubin found that GDF11 also encourages growth of new blood vessels and olfactory neurons in the mouse brain.

To explain the so - called angiogenic switch, or sudden growth of new blood vessels, some have pointed to endothelial progenitors, which live in bone marrow but are found in more than half of all solid tumor types, says hematology oncologist Shahin Rafii of Weill Cornell Medical College in New York City.

More than 90 percent of patients with either high nm23, a protein that prevents the cancer from spreading, or low angiogenesis, minimal growth of new blood vessels to supply the budding tumor, were alive an average of 14 years after treatment, compared to only 70 percent of those with low nm23 or high vessel density.

Recent studies have shown that curcumin can reduce growth of new blood vessels in tumors and metastasis and basically help kill off cancerous cells.

Endurance exercise activated genes that stimulated growth of new blood vessels and increased endurance.

One was obesity, in part because an earlier study had suggested that giving rodents angiogenesis inhibitors, drugs that prevent growth of new blood vessels, could help them lose weight.

This happens because the loss of blood flow in a vessel causes the local oxygen level to drop, which stimulates local production of vascular endothelial growth factor, or VEGF, a protein which in most tissues causes the growth of new blood vessels to repair damage.

The team found 12, including ANG1, which controls the growth of new blood vessels.

«TRINOVA - 1 also showed that angiogenesis is a complex process in oncology and many new targets like angiopoietin 1/2 will allow us to more effectively inhibit the growth of new blood vessels that are necessary for cancer growth, metastases and progression.

Trebananib (formally known as AMG 386; Amgen) is a first - in - class peptide - Fc fusion protein (or peptibody) that targets angiogenesis (the growth of new blood vessels into cancerous tumors) by inhibiting the binding of both angiopoietin 1 and 2 to the Tie2 receptor.

The sunshine vitamin has been linked to several anticancer effects, such as inhibiting the proliferation of tumor cells and limiting the growth of new blood vessels that feed expanding tumors.

Anti-Apelin and anti-Elabela drugs could potentially inhibit the growth of new blood vessels to counter disorders such cancer and diabetic retinopathy, the leading cause of new blindness in working adults in developed countries, including Singapore.

The experimental drug cediranib blocks the cell surface receptor VEGF, which stimulates the growth of new blood vessels to feed the growth of tumours,» explains study researcher Dr Paul Symonds, of the Department Cancer Studies & Molecular Medicine at the University of Leicester, UK.

Two subsequent studies by Wagers and her colleagues found that GDF11 boosted the growth of new blood vessels and neurons in the brain and spurred stem cells to regenerate skeletal muscle at the sites of injuries.

Part of the BAI1 protein can stop the growth of new blood vessels, which growing cancers need.

This observation led researchers to develop antiangiogenesis drugs that inhibit the growth of new blood vessels.

Angiogenesis inhibitors prevent the growth of new blood vessels and have long been investigated as a way to stop tumor growth.

«This novel combination therapy simultaneously targets multiple pathways contributing to metastasis» explains Professor Augustin, «On the one hand, we inhibit the growth of new blood vessels in metastases.

Sustained angiogenesis, the growth of new blood vessels, and the suppression of the immune system are hallmarks of cancer, with an increasing amount of evidence demonstrating that these two activities are interrelated.

While the use of antiangiogenesis drugs that block the growth of new blood vessels can improve the treatment of some cancers, clinical trials of their ability to prevent the development of new metastases have failed.

Yeasts are single - celled and bloodless, yet they carry genes that orchestrate the growth of new blood vessels in vertebrates.

Unfortunately, the retina is such a complex and highly ordered tissue that the in - growth of these new blood vessels causes more visual loss than the original degenerative process.

This cancer is characterized by the growth of new blood vessels, known as angiogenesis.

They also know little about one of the drug's benefits: Thalidomide appears to control angiogenesis, the growth of new blood vessels.

Earlier studies by Basu and others have shown that dopamine blocks the growth of new blood vessels in tumors by inhibiting the action of vascular endothelial growth factor - A (VEGF - A).

One of the first treatments of this type, developed as early as 2004, specifically aims at slowing the growth of new blood vessels and at preventing neovascularisation of tumours.

This happens because the loss of blood flow in a blood vessel causes the local oxygen level to drop, which stimulates local production of vascular endothelial growth factor, or VEGF, a protein that in most tissues causes the growth of new blood vessels to repair damage.

They found that these drugs suppressed the growth of new blood vessels, reduced the numbers of bacteria, and limited the spread of TB outside the granulomas.

«In a young, healthy individual, hypoxia — low oxygen levels — triggers the body to make factors that help coordinate the growth of new blood vessels but this process doesn't work as well as we age,» says Gregg Semenza, M.D., Ph.D., professor of pediatrics and genetic medicine and director of the vascular biology program at the Johns Hopkins Institute for Cell Engineering.

Avastin works by slowing the growth of new blood vessels needed by cancer tumours to grow.

They are also commonly referred to as «repair cells» for their ability to heal injured organs or body parts by accelerating tissue repair and regeneration, decreasing inflammation as well as increasing blood flow through the growth of new blood vessels.

The researchers said that the association between the fine particulate matter and cancer could be the result of damage to the body's DNA - repair function, changes in the immune response or inflammation that triggers the growth of new blood vessels fueling the spread of tumors.

Those fragments stimulate the growth of new blood vessels and help tumor cells grow and migrate.

By stimulating the growth of new blood vessels, promoting anti-inflammatory effects, recruiting cells toward tissue regeneration and inhibiting further cell death, adult stem cells can restore some function to damaged or diseased heart muscle.

These cells are then delivered to the heart via infusion into the coronary sinus, where they prompt the growth of new blood vessels.

Cardiac cell therapy stimulate the growth of new blood vessels in the heart to help restore blood flow to your heart.

Other research has shown that oxygen - deprived cells in the retina produce a type of protein called vascular endothelial growth factor (VEGF), which triggers the growth of new blood vessels in the retina.

Medical research has shown adult stem cells to be angiogenic, meaning they stimulate the growth of new blood vessels.

Okyanos treatment targets the damaged heart tissue and stimulates the growth of new blood vessels through the process of angiogenesis using adult adipose -(fat) derived regenerative cells.

The growth of new blood vessels tends to occur quite early for most cancers; even small tumors found via mammogram frequently have a high microvessel count (MVC).

Some are involved in angiogenesis (the growth of new blood vessels).

In retinal diseases including age - related macular degeneration (AMD) and diabetic retinopathy, the growth of new blood vessels damages the retina and causes blindness.

Among many other important biological and immunological functions, Growth Factors cause the growth of new blood vessels, connective and nerve tissues by the activation of Stem Cells that are normally found in all parts of the human body.

Current examples include Coherence Optical Tomography (OCT), which has revolutionized the field of Ophthalmology by allowing the early diagnosis of macular degeneration (MD) in the retina, and Photodynamic Therapy (PDT) approaches for treatment of cancers by retarding the growth of new blood vessels and vasculature.

These special healing cells also hold as their primary mechanism the growth of new blood vessels which restores the flow of oxygen - rich blood to the brain for a wide spectrum of healing benefits.

For instance, exercise seems to change brain structure, stimulating the growth of new blood vessels and nerve cells.