Sentences with phrase «growth of organoids»

ANN ARBOR, Mich — By combining engineered polymeric materials known as hydrogels with complex intestinal tissue known as organoids — made from human pluripotent stem cells — researchers have taken an important step toward creating a new technology for controlling the growth of these organoids and using them for treating wounds in the gut that can be caused by disorders such as inflammatory bowel disease (IBD).

In addition to allowing growth of organoids within the engineered hydrogel in a tissue culture incubator, the research team demonstrated that the hydrogel could act like glue, allowing organoids to stick in place and contribute to wound healing when transplanted into an injured mouse intestine.

Not exact matches

The 2 - millimeter organoids survived for at least two months, Chen said in an interview, and showed «extensive» growth of human axons into the rat brain.

«Damaging consequences of Zika virus infection in human minibrains: Zika virus reduces growth, induces cell death, malformations in human neurospheres, brain organoids.»

For pluripotent stem cells, that means exposing them to just the right growth factors or inhibitors at just the right times, over about a month, says James Wells of the Center for Stem Cell and Organoid Medicine at Cincinnati Children's Hospital Medical Center.

Day 56: Organoids are again snipped in half and transferred to new petri dishes made of oxygen - permeable plastic to optimize access to oxygen for healthy growth.

After infecting these organoids with the Zika virus, the researchers observed a collapse of cortexlike tissue that may partly explain the stunted brain growth (SN: 4/2/16, p. 26).

Because those organoids include stroma, a scaffold of connective tissue essential for tumor growth, they may prove better for studying therapies that target the stroma, such as cancer immunotherapy.

A major challenge in creating any type of organoid is determining the unique mixture of nutrients, growth factors, and tissue culture techniques that will transform patient tumor cells into miniature tumor organoids in a petri dish.

Stem cell technology has advanced so much that scientists can grow miniature versions of human brains — called organoids, or mini-brains if you want to be cute about it — in the lab, but medical ethicists are concerned about recent developments in this field involving the growth of these tiny brains in other animals.

AMSBIO announces the availability of two new formulations of Basement Membrane Extract (BME) known as Cultrex BME 2 (organoid growth matrix) and Cultrex BME 3 (xenograft / tumorgraft matrix).

Genetic inactivation of MEKK3 or p38d mimics that of p62 in that it leads to inhibited growth of PTEN - deficient prostate organoids.

In the organoids that Lancaster had derived from a healthy person, the growth of the hindbrain slowed as the forebrain grew — reflecting what happens as a normal human fetal brain develops.