Sentences with phrase «guanine nucleotide binding»

β - Arrestins, originally discovered in the context of heterotrimeric guanine nucleotide binding protein — coupled receptor (GPCR) desensitization, also function in internalization and signaling of these receptors.

Not exact matches

Heterotrimeric guanine nucleotide - binding regulatory proteins (G proteins) dissociate into guanosine triphosphate (GTP)- bound alpha subunits and a complex of beta and gamma subunits after interaction with receptors.

The β2 - adrenergic receptor (β2AR) is a well - studied prototype for heterotrimeric guanine nucleotide — binding protein (G protein)-- coupled receptors (GPCRs) that respond to diffusible hormones and neurotransmitters.

Hormones and neurotransmitters may mediate common responses through receptors that couple to the same class of heterotrimeric guanine nucleotide — binding (G) protein.

Heterotrimeric guanine nucleotide — binding protein (G protein)-- coupled receptors constitute the largest family of eukaryotic signal transduction proteins that communicate across the membrane.