Sentences with phrase «guanosine tetraphosphate»

Sildenafil affects cyclic guanosine monophosphate (cGMP), which is found in areas such as the corpus cavernosum and pulmonary vasculature.

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Nucleotides: cytidine 5» - monophosphate, disodium guanosine 5» - monophosphate, disodium uridine 5» - monophosphate, adenosine 5» - monophosphate; 10.

If you have more nitric oxide, you will make more guanosine monophosphate (cGMP) which will give you a harder erection.

EDR activity involves the release of endothelial nitric oxide (NO) release and subsequent increase in cyclic guanosine monophosphate (GMP) levels in the vascular smooth muscle cells ultimately increasing vasodilation and blood flow.

A purine nucleotide biosynthesis enzyme guanosine monophosphate reductase is a suppressor of melanoma invasion.

Borrelia burgdorferi rel Is Responsible for Generation of Guanosine - 3» - Diphosphate - 5» - Triphosphate and Growth Control

Pharmacological targeting of guanosine monophosphate synthase suppresses melanoma cell invasion and tumorigenicity.

Strauss and his colleagues postulate that both neurotransmitters together with cyclic guanosine monophosphate (cGMP) form the perfect storage media for short - term memories.

Examples include cytidine, uridine, adenosine, guanosine, thymidine and inosine.

This long - range interaction connects a sequence adjacent to the guanosine - binding site with the domain implicated in coordinating the 5 ′ splice site helix, and it thereby contributes to formation of the active site.

It also binds to the guanosine triphosphatase (GTPase) Ran in its guanosine diphosphate (GDP)- bound form and to karyopherin β.

Beta tubulins can selectively (and reversibly) allow GTP to hydrolyze; they take on water to become guanosine diphosphate (GDP).

Sildenafil, the active ingredient in Viagra, is known to inhibit the degradation of cyclic guanosine monophosphate (cGMP), a messenger molecule that advances the body clock in response to light.

The guanosine triphosphatase (GTPase) dynamin builds up membrane stress by polymerizing into a helical collar that constricts the neck of budding vesicles.

The newly published paper identifies ppGpp (guanosine - 3», 5» -(bis) pyrophosphate), a compound related in structure to the guanine building block of DNA, as the central controller of UvrD - driven backtracking in the NER pathway.

Dynamin is the prototypical member of a large family of structurally related guanosine triphosphatases involved in membrane fission and fusion.

The analyses revealed a strong preference for the cytidine and guanosine bases at the ribonucleotide sites.

These actions are specific for the sympathetic and parasympathetic neurotransmitters and for the two cyclic nucleotides, as phenylephrine, tyramine, choline, adenosine 5» - monophosphate and guanosine 5» - monophosphate do not inodify lysosomal enzyme release.

Osmotic release of β - glucuronidase from polymorphonuclear leukocyte lysosomes is inhibited by catecholamines and adenosine 3», 5» - monophosphate, and accelerated by cholinergic agents and guanosine 3», 5» - monophosphate.

The excised intervening sequence retains the branch site and terminates in a guanosine residue with a 3» hydroxyl group.

Guanosine can then easily be made from this.

The biggest sticking point was that until now, no one had identified a plausible way to generate the two purine nucleosides, adenosine and guanosine — A and G in the genetic code.

Elongation factor G (EF - G) is a guanosine triphosphatase (GTPase) that plays a crucial role in the translocation of transfer RNAs (tRNAs) and messenger RNA (mRNA) during translation by the ribosome.

Auriel Willette, an assistant professor of food science and human nutrition; and Joseph Webb, a graduate research assistant, found on average that Caucasians with one bad version of the gene — guanosine triphosphate cyclohydrolase - 1 or GCH1 — developed Parkinson's symptoms five years earlier, and had a 23 percent increased risk for the disease.

Cigarette smoke activates guanylate cyclase and increases guanosine 3», 5» - monophosphate in tissues

The mth gene predicted a protein with homology to several guanosine triphosphate — binding protein — coupled seven — transmembrane domain receptors.

The magic spot subsequently was shown to be guanosine tetraphosphate, or ppGpp, a chemically modified analog of the G nucleotide in the ATCG alphabet of the genome.

This signaling pathway is dependent on a molecule that plays an important role in bacterial stress response: Guanosine tetraphosphate.

This cellular machinery translates its sequence of four kinds of nucleosides — adenosine, cytidine, uridine, and guanosine — into a protein.

The dynamic instability that makes it possible for microtubules to transition from a rigid polymerized or «assembled» nucleotide state to a flexible depolymerized or «disassembled» nucleotide state is driven by guanosine triphosphate (GTP) hydrolysis in the microtubule lattice.

Mochly - Rosen and colleagues identified several other potential biomarkers that were elevated in HD model mice, including the levels of 8 - hydroxy - deoxy - guanosine, a product of oxidative DNA damage, in the urine and the presence of mutant huntingtin aggregates and oxidative damage in muscle and skin cells.

Heterotrimeric guanine nucleotide - binding regulatory proteins (G proteins) dissociate into guanosine triphosphate (GTP)- bound alpha subunits and a complex of beta and gamma subunits after interaction with receptors.

REPAIR has the ability to target individual RNA letters, or nucleosides, switching adenosines to inosines (read as guanosines by the cell).