Sentences with phrase «guidance cues»
"Guidance cues" refer to signals or signposts that provide direction or instructions to guide someone or something in a particular way. They help to steer or lead a person or entity towards a desired target or objective. Full definition
The 5X will even display guidance cues for upcoming turns.
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In collaboration with the Program in Neuroengineering at McGill University, Dr. Charron's team developed an innovative technique to recreate the concentration gradients of guidance cues in vitro, that is to say they can study the developing axons outside their biological context.
To do so, they studied the relative change in concentration of guidance cues in the neuron's environment, which is referred to as the steepness of the gradient.
Currently, students in my lab are using molecular biology to clone the genes for guidance cues from crickets.
«To reach their target, growing axons rely on molecules known as guidance cues, which instruct them on which direction to take by repelling or attracting them to their destination,» explains Dr. Charron, Director of the Molecular Biology of Neural Development research unit at the IRCM.
In this paper, IRCM scientists uncovered how axons use information from multiple guidance cues to make their pathfinding decisions.
We study cell (endothelial cells, fibroblasts, osteoblasts) guidance cues on biodegradable scaffolds (e.g. polymers).
Elizabeth Sheldon - The role of semaphorin as a molecular guidance cue for dendritic regeneration in the cricket auditory system
In those instances, we revealed that a combination of guidance cues can behave in synergy with one another to help the axon interpret the gradient's direction.»
Over the past few decades, the scientific community has struggled to understand why more than one guidance cue would be necessary for axons to reach the proper target.
«We found that the steepness of the gradient is a critical factor for axon guidance; the steeper the gradient, the better the axons respond to guidance cues,» says Tyler F.W. Sloan, PhD student in Dr. Charron's laboratory and first author of the study.
«In addition, we showed that the gradient of one guidance cue may not be steep enough to orient axons.
Award Recipient: Jason G. Cyster, HHMI, Univ. of California, San Francisco Deciphering the guidance cue code for B cell immunity