But other lipids are known to
guide cell migrations in human brain development, and geneticist Ken Howard of University College London suspects HMG - CoA reductase might help produce a similar lipid molecule or modify a protein that attracts the germ cells.
One way this communication happens is through the ephrin / Eph - receptor system, which is able to
guide cell migration and the growth of neuronal extensions.
Not exact matches
In order to find the genes that
guide that
migration, geneticist Ruth Lehmann of the Howard Hughes Medical Institute at New York University Medical School and her colleagues used chemicals to cause mutations in thousands of adult fruit flies then screened their embryonic offspring for lost or misguided germ
cells.
Early in his career, he discovered that previously enigmatic support
cells, known as radial glia, serve as
guides for the
migration of cortical neurons in the developing brain, and showed how this process is critical for the organization of the multi-layered structure of the cerebral cortex.