Sentences with phrase «guide drug design»
Further, she has begun collaborative work with Schrødinger to determine if it is possible to add new computational tools to the suite that will help guide drug design with resistance in mind early on in the design process.
https://sbgrid.org/
«How cytoplasm «feels» to a cell's components: In study that may guide drug design, researchers find organelles encounter varying levels of resistance.»
Not exact matches
Dr Baker explained: «Our work has implications not only for understanding the basic science of protein folding and stability, but also for guiding the design and engineering of new proteins and drug molecules.»
«Having the structure of the full - length Zika NS1 provides new information that can help guide the design of a potential vaccine or antiviral drugs,» said senior author Janet Smith, director of the Center for Structural Biology at the U-M Life Sciences Institute, where her lab is located, and professor of biological chemistry at the U-M Medical School.
This research on these protein clusters, or aggregates as scientists call them, could help guide design of new anticancer drugs.
The ability to design new protein nanostructures could have useful implications in targeted delivery of drugs, in vaccine development and in plasmonics — manipulating electromagnetic signals to guide light diffraction for information technologies, energy production or other uses.
Figuring out these details, says Sisodia, will guide the design of drugs that might slow the progression of Alzheimer's.
This approach, in which structure and activity is not linked to a specific protein target, can cause other difficulties and slow the progress of discovery, not least because of the difficulty of assessing relevant toxicity against host mechanisms and the inability to use structure - guided drug - design to drive Medicinal Chemistry progress.
Combined with our structures, the screening data is enabling us to identify potential chemical selectivity cues that can be used for structure - guided design of selective anti-parasitic drug candidates.