Two studies published on July 9th in PLOS Pathogens provide results on Nabs that could help
guide vaccine design.
Not exact matches
«Having the structure of the full - length Zika NS1 provides new information that can help
guide the
design of a potential
vaccine or antiviral drugs,» said senior author Janet Smith, director of the Center for Structural Biology at the U-M Life Sciences Institute, where her lab is located, and professor of biological chemistry at the U-M Medical School.
The ability to
design new protein nanostructures could have useful implications in targeted delivery of drugs, in
vaccine development and in plasmonics — manipulating electromagnetic signals to
guide light diffraction for information technologies, energy production or other uses.
For 30 years, researchers have struggled to determine which immune responses best foil HIV, information that has
guided the
design of AIDS
vaccines and other prevention approaches.
For the published request for applications, see the May 18, 2016
Guide announcement, Partnerships for Structure - Based
Design of Novel Immunogens for
Vaccine Development (R01).
Dr. Schief's work focuses on computation -
guided and structure - based
design of immunogens and immunization regimens, with the goal of inducing broadly neutralizing antibodies against HIV and other pathogens that have frustrated traditional
vaccine design strategies.
All this information is being mined to
guide the
design and development of a new and perhaps more potent generation of AIDS
vaccine candidates.
Guided by the Behavioral
Vaccine Theory of prevention, this study uses a no - control group
design to examine intervention variables that predict favorable changes in depressive symptoms at the six - to - eight week follow - up in at - risk adolescents who participated in a primary care, Internet - based prevention program.