5 - HT1 receptors are expressed by type II taste cells and 5 - HT3 receptors are hypothesized to be expressed in
gustatory nerve fibers (Jackson and Yakel, 1995; Wang et al., 2002).
Postsynaptic P2 × 3 - containing receptors in
gustatory nerve fibres mediate responses to all taste qualities in mice
All taste fibers express ionotropic purinergic (P2X) receptors (Bo et al., 1999; Ishida et al., 2009) that are required for transmission from taste receptor cells to the afferent nerves; genetic deletion or pharmacological blockade of the P2X2 and P2X3 receptors expressed by
the gustatory nerve fibers eliminates chorda tympani nerve responses to all taste stimuli (Finger et al., 2005; Ohkuri et al., 2012; Jaber et al., 2014; Vandenbeuch et al., 2015).
First and foremost, amarogentin, a monoterpene, has antibacterial and antifungal attributes, and is also mainly responsible for the plant's highly bitter taste that stimulates
the gustatory nerves in the mouth, increasing saliva production and appetite.
Not exact matches
In the present study, we demonstrate that a subset of
gustatory sensory neurons express functional 5 - HT3 receptors that play a significant role in the neurotransmission of taste information from taste buds to
nerves.
We investigated whether
gustatory afferents express functional 5 - HT3 receptors and, if so, whether these receptors play a role in transmission of taste information from taste buds to
nerves.
Somatosensory innervation of these taste fields arises from the trigeminal
nerve; therefore, cells of the geniculate ganglion that innervate taste fields are
gustatory rather than somatosensory in function.
The majority of cells of the geniculate ganglion are
gustatory, contributing to the chorda tympani and greater superficial petrosal
nerves (Foley and DuBois, 1943; van Buskirk, 1945) innervating, respectively, fungiform papillae and palatal taste fields.