Many studies in mouse models, and more recent research among human populations as well, have correlated differences in
gut microbe populations with risks of developing the autoimmune condition.
That alters
gut microbe populations, triggering the activity of pro-inflammatory T cells, which cause further damage in the brain, mouse studies show.
A failure of immune cells to keep
the gut microbe population in check can lead to chronic gut inflammation, manifesting as IBD.
Where
the gut microbe population is thought to be unbalanced (e.g. over-growths), or even have extinctions, a course of a quality high - potency probiotic might be useful.
Not exact matches
In the new study, they treated the mice with antibiotics to disrupt the
populations of
microbes living in their
gut.
A more normal
population of
microbes in the
gut can offset the bad players.»
Along with a postdoc in Kaplan's lab, Alice Liou, they decided to test whether the surgery itself caused the changes in the
population of
gut microbes — known as the microbiota.
Moeller is beginning to assemble a snapshot of the
microbes in the
guts of our ancient ape ancestor — in essence, a paleo
gut that fit our paleo diet — and hopes to go even further back in time if, as seems likely, all mammals have evolved their unique microbiota from a common ancestral
population in the distant past.
Quantifying the relative abundances of three ubiquitous genera of
gut microbes — Bacteroides, Lactobacillus and Bifidobacterium — revealed that
populations of Bacteroides andLactobacillus peter out in a predictable manner, the team reported in June in the Journal of Forensic Sciences.
To test whether a partial loss of plant - derived dietary fiber would result in a partial loss of native
gut microbes, the authors also collected fecal samples from a semi-captive
population of red - shanked doucs who lived in a sanctuary and received about half of the normal variety of plants eaten by wild doucs.
Rheumatoid arthritis patients have less diversity in their
gut microbes than does the general
population, and appear to have an abundance of certain
gut bacteria whose numbers are rare in healthy people.
Warinner and colleague, Cecil M. Lewis, Jr., co-direct OU's Laboratories of Molecular Anthropology and Microbiome Research and the research focused on reconstructing the ancestral human oral and
gut microbiome, addressing questions concerning how the relationship between humans and
microbes has changed through time and how our microbiomes influence health and disease in diverse
populations, both today and in the past.
The ancient dung, shown in the above picture, contains
gut microbes that provide clues to the two
populations» diets.
The
gut microbiome is the
population of
microbes living within the human intestine, consisting of tens of trillions of microorganisms (including at least 1,000 different species of known bacteria).
Still, since only a fraction of the symbiont
population is harvested, the
microbes likely benefit from the association with the host by gaining nutrition in the bug's
gut and a secured transmission route to the next generation,» says Hassan Salem.
With crowdfunded projects such as American
Gut, which already has thousands of participants who have had their microbiomes sequenced, and studies of people whose lives are very different from modern Western civilization, such as the Hadza of Tanzania, Yanomami of Venezuela and Matsés of Peru, we may be able to replenish our ancestral
microbes and discover new ones that help to maintain health for individuals or entire
populations.
By joining American
Gut, your sample and diet and lifestyle data will be merged with thousands of other folks and will allow us to explore
population - level patterns that will hopefully lead to a better understanding of why we carry the
microbes we carry and what aspects of our behavior and disease state drive these microbial patterns.
BACTERIA AND OTHER
MICROBES interact in diverse
populations everywhere from the human
gut to the oceans.
A new study shows that pregnancy alters
microbe populations in the
gut.
The researchers now hypothesize that
microbes in the
gut, where most of this pTreg cell
population is switched on, may be responsible for generating these protective cells and thus protecting against the autoimmune attack on pancreatic beta cells that cause type 1 diabetes.
The bigger picture is that «human
gut -
microbe populations fall into three distinct categories....
This indicates they may be promoting different species of bifidobacteriaand probably other
gut microbes within the complex
gut microbial
population.
«In a series of experiments conducted with mice prone to intestinal inflammation, the researchers found that inflammation itself causes significant simplification in diverse communities of
gut microbes and allows new bacterial
populations to establish major footholds.
Use probiotics: Live, «friendly» bacteria that bolster your
gut's
population of healthy
microbes.
Another important strategy for fighting reflux naturally is to eat food that increases the
population of healthful
gut microbes.
These will help recolinize the
gut with correct
populations of beneficial
microbes.
As probiotic
microbes become more dominant in the
gut, normal whole foods can gradually be restored, allowing a probiotic bacterial
population to grow in place of the pathogenic bacteria.
What current research shows is a more diverse
population of
gut microbes is better.
In my previous article, I described how each of us possesses a
gut microbiota with a unique
population of
microbes and that our uniqueness may influence the efficacy of the probiotic supplements that we use.
When a dog eating kibble is first introduced to lean raw diets with vegetables, she may not have the
gut microbes (mostly bacteria) to get the most out of the food, and will still have a large
population of
gut microbes that feed on high - carbohydrate grains or starches that are not in Darwin's or in the dog's natural diet.
It takes time to increase the
gut microbes we want and decrease the
microbe population of those we don't want.