Sentences with word «haematopoietic»

This study provides an experimental system to further understand how benzene metabolites impair the regulation of haematopoietic stem cells, the researchers say.

Specifically, the project will seek to characterize genetic variants regulating the processes of differentiation, proliferation and fate determination in the human haematopoietic system.

Luc Douay at Pierre and Marie Curie University, Paris, and his colleagues extracted what are called haematopoietic stem cells from a volunteer's bone marrow.

Dr. Sogame particularly enjoys the challenges of Haematopoietic tumors, small molecule inhibitors / targeted therapy and palliative care, with the improvement of quality of life being the primary goal.

These cells — known as haematopoietic stem cells (HSCs)-- help to restore blood supply in patients who have been treated for leukemia.

No studies to - date have compared the toxic effects of 1,4 - BQ exposure on different haematopoietic progenitors, the researchers say.

Flach J, Bakker ST, Mohrin M, et al., Replication stress is a potent driver of functional decline in ageing haematopoietic stem cells.

Mossadegh - Keller N, Sarrazin S, Kandalla PK, Espinosa L, Stanley RE, Nutt SL, Moore J, Sieweke MH M - CSF instructs myeloid lineage fate in single haematopoietic stem cells.

Runx1 seems to participate in the fate decision in favor of haematopoietic development.

The trial will be using ex vivo haematopoietic stem cells from patients, which can be edited under in vitro conditions in the lab.

These cells return to a precursor stage following their spontaneous fusion with transplanted haematopoietic stem and progenitor cells in damaged retinas.

Is it feasible to conduct a randomised controlled trial of pretransplant exercise (prehabilitation) for patients with multiple myeloma awaiting autologous haematopoietic stem cell transplantation?

Recently, working with many colleagues, the Penn team published in Nature the first application of 2PLM to directly quantify the physiological environment of blood stem cells, called haematopoietic stem cells, or HSCs.

Pathology and genetics of tumors of haematopoietic and lymphoid tissues.

The team studied the effects of 1,4 - BQ on «haematopoietic stem cells» (HSCs are stem cells found in the bone marrow that can give rise to any kind of blood cell) and «haematopoietic progenitor cells» (each HPC in the bone marrow can differentiate into only one specific type of blood cell) in mice.

In humans, these DCs can be derived from lineage (Lin)- haematopoietic stem cells from the peripheral blood.

Haematopoietic and endothelial cells arise from a common precursor, commonly referred to as the haemangioblast.

«The ability to manufacture HSCs» — haematopoietic, or blood, stem cells — «in the laboratory holds enormous promise for cell therapy, drug screening and studies of leukaemia development,» they wrote in a commentary, also published by Nature.

Specific projects in the field of Medical Systems Biology / Mathematical Modelling include the investigation of stem cell - niche (i.e. local growth environment) interactions, the analysis and the prediction of clonal competition processes, as well as the modelling of aging - related phenomena in the haematopoietic system.

Haematopoietic stem cell differentiation promotes the release of prominin - 1 / CD133 - containing membrane vesicles - a role of the endocytic - exocytic pathway.

Haematopoietic stem cells are found in the bone marrow and give rise to all the blood cell types.

Indeed this sort of model has been used to explain the existence of a stable attractor and associated lineage primed states in EML cells, a haematopoietic progenitor cell line [54], and as the basis for heterogeneity in Nanog expression in ES cells [11].

The team's next step will be to image oxygen along with other metabolites and simultaneously visualize the haematopoietic stem cells themselves as they inhabit the niche.