The AG
haplotype showed significantly greater expression of luciferase than the GT haplotype.
On further culture or after subcloning this ES cell line at various times (passages), this particular mtDNA
haplotype showed essentially random drift, with cells carrying anything from 0 to 100 %.
Not exact matches
(Previous studies have
shown that
haplotype patterns differ in part based on ancestry.)
«We also
showed haplotype H was associated with a reduction in the number of copies of the mitochondrial DNA in cells, which might indicate that mitochondria in those cells are more efficient,» Professor Sherwin said.
In 2010, Lo
showed that with both parents»
haplotypes known, it would be possible to predict the child's genome from the DNA in an expectant mom's blood.
We also
show that most autosomal
haplotypes associated with domestication were already established in our Neolithic dogs, but that adaptation to a starch - rich diet likely occurred later.
Altogether, the
haplotypes of the three ancient samples were classified as either dog or wolf - like for 18 matrices that
showed clear distinction between dog and wild canid
haplotypes based on average reference allele counts calculated per window.
This analysis
showed differential expression associated with the
haplotypes at both loci, suggesting the risk
haplotypes are associated with an effect on T - cell response.
«Seven out of eight ES cell lines derived from (parthenogenetic) embryos after MRT (spindle transfer)
showed no or very low persistence of the mtDNA
haplotype that was carried over with the nuclear DNA.
Hirano, Egli and colleagues have
shown that in unusual cases, stem cell clones derived from MR eggs can
show substantial drift towards the donors mtDNA
haplotype after low level mtDNA carryover during the MR procedure.
However, one line
showed a significant increase in the proportion of the carried - over mtDNA
haplotype compared with that in the enucleated egg.
Haplotype analyses
showed similar results.
The role of HLA
haplotypes in celiac disease will be used to
show the role of deamidation in celiac disease and how this is not a process that happens with the non-celiac gluten sensitivity form.
The graph
shows the number of
haplotypes found in a survey of each breed, separated into Class I and Class II DLA.
In the Springer spaniel, the DLA - DRB1 * 015:01 — DQA1 * 006:01 — DQB1 * 023:01
haplotype was significantly associated with disease risk (p = 0.014, odds ratio (OR) = 5.14) and
showed a similar trend in the Cocker spaniel.
Haplotypes identified in affected dogs are
shown.
SNP
haplotypes spanning 3 genes were consistent with autosomal recessive transmission, and microsatellite data
showed that only the segment encompassing COLQ was inherited IBD.
Island foxes
show greater mitogenome diversity in the northern islands with nine
haplotypes that differ from 2 — 5 base pairs from the central node of the star - shaped radiation (Fig. 2).
Consistent with the pathogenetic hypothesis of increased serotonin transporter activity in OCD, we
showed that a
haplotype containing the higher - expressing allele at each of several SLC6A4 loci is significantly associated with increased genetic susceptibility to OCD.
While Dutch researchers have failed to replicate this association [97, 98], parental genetic data and family - based analyses in the Hungarian sample
showed a highly significant non-transmission of the 7 - repeat allele (and the -521 T ~ 7 - repeat
haplotype) to securely attached infants, as well as a trend for preferential transmission to disorganised infants [95].