Allele frequencies in regions on the 13 chromosomes
harboring candidate genes were evaluated for a pattern consistent with a recessive trait (Table S2).
Not exact matches
Genomic regions known to
harbor CMS
candidate genes were screened for case allele frequencies of 1.0 and control allele frequencies of between 0.14 and 0.50.
Through the examination of SNP allele frequencies in the Labrador Retriever family, we identified 2 chromosomes
harboring CMS
candidate genes that showed an inheritance pattern consistent with autosomal recessive transmission.
In the absence of a population suitable for GWAS, we utilized genome - wide SNP profiles from a nuclear family to evaluate inheritance patterns in chromosomal regions
harboring all 18
candidate genes.