Sentences with phrase «health model of disease»

An award - winning cancer investigator and defender of the welfare of newborn children, Perera comes from the public - health model of disease, which assumes that most ailments are conveyed from outside the body and can be prevented.

Not exact matches

«Future studies need to determine the health effects of these cocoas in models of human disease and to evaluate the consumer acceptability of the cocoas as part of a chocolate product.»

More broadly, updated longitudinal studies of the natural history of hypertension, diabetes, and cardiovascular disease are needed, because the data from the National Health and Nutrition Examination Survey that we used in our model are somewhat dated.

Of note, our models may underestimate the true maternal costs of suboptimal breastfeeding; we modeled the effects of lactation on only five maternal health conditions despite data linking lactation with other maternal health outcomes.46 In addition, women in our model could not develop type 2 diabetes mellitus, hypertension, or MI before age 35 years, although these conditions are becoming increasingly prevalent among young adults.47 Although some studies have found an association between lactation and rates of postmenopausal diabetes22, 23 and cardiovascular disease, 10 we conservatively limited the duration of lactation's effect on both diabetes and MOf note, our models may underestimate the true maternal costs of suboptimal breastfeeding; we modeled the effects of lactation on only five maternal health conditions despite data linking lactation with other maternal health outcomes.46 In addition, women in our model could not develop type 2 diabetes mellitus, hypertension, or MI before age 35 years, although these conditions are becoming increasingly prevalent among young adults.47 Although some studies have found an association between lactation and rates of postmenopausal diabetes22, 23 and cardiovascular disease, 10 we conservatively limited the duration of lactation's effect on both diabetes and Mof suboptimal breastfeeding; we modeled the effects of lactation on only five maternal health conditions despite data linking lactation with other maternal health outcomes.46 In addition, women in our model could not develop type 2 diabetes mellitus, hypertension, or MI before age 35 years, although these conditions are becoming increasingly prevalent among young adults.47 Although some studies have found an association between lactation and rates of postmenopausal diabetes22, 23 and cardiovascular disease, 10 we conservatively limited the duration of lactation's effect on both diabetes and Mof lactation on only five maternal health conditions despite data linking lactation with other maternal health outcomes.46 In addition, women in our model could not develop type 2 diabetes mellitus, hypertension, or MI before age 35 years, although these conditions are becoming increasingly prevalent among young adults.47 Although some studies have found an association between lactation and rates of postmenopausal diabetes22, 23 and cardiovascular disease, 10 we conservatively limited the duration of lactation's effect on both diabetes and Mof postmenopausal diabetes22, 23 and cardiovascular disease, 10 we conservatively limited the duration of lactation's effect on both diabetes and Mof lactation's effect on both diabetes and MI.

The response in Newburgh was crafted in consultation with the U.S. Centers for Disease Control and Prevention and will serve as a national model for understanding PFOS exposure, state Department of Health spokesman James Plastiras said.

«It started to become quite evident to me that a research career in infectious disease epidemiology and mathematical modeling would be a fairly perfect combination of my longstanding interests in math and biology and medicine, as well as my emerging interest in infectious disease transmission and public health more generally,» she says.

Reductions in biodiversity from illegal wildlife trade can have other substantial negative human health impacts, including the loss of potential sources of pharmaceuticals, experimental models for studying disease, crop pollination and micronutrients for humans lacking alternative sources of protein.

Combined, these models give public health and governmental officials vital climate information needed to create early warning systems — systems that can alert the public to the risk for disease and allow public health officials to mobilize resources and enact mosquito control programs and surveillance ahead of peak season.

Both of the advantages point toward a possibility of using this new method for regenerative therapies and for creating models of rare diseases for future studies and individualized health care.

He originated the Barker Hypothesis, also known as the Developmental Origins of Health and Disease model, linking fetal and early infant experiences to an individual's health status across the lifHealth and Disease model, linking fetal and early infant experiences to an individual's health status across the lifhealth status across the lifespan.

Researchers at RTI International will continue to further refine their model to incorporate other national health issues, such as obesity, and to also assess how positive interventions could alter the course of kidney disease in America.

«The mouse models don't recapitulate the human disease,» said Ravi Basavappa of the National Institutes of Health, which gave Fine one of its 12 Pioneer Awards for «unusually bold,» high - risk, and potentially high - impact research.

the National Institutes of Health being the biggest funder but in the case of the flu, the Centers for Disease Control also fund their own research and a little bit about that research, and other countries also have their own ways of funding things, typically government, and the researchers in their current model of working, they are not required to release their scientific data until they publish it.

In order to an early detection or a correct medication of potentially chronic diseases, we need more efficient models in the primary health care to identify those who are at risk.

An international research team led by biochemists at The University of Texas Health Science Center at Houston (UTHealth) reduced the sickling of red blood cells in a mouse model of the disease.

«So now that we have seen this environmental toxicant - induced inflammation, we can study the beneficial anti-inflammatory foods, like the purple potato and others, in this human development model, and see how a mother's health and her levels of toxicants and beneficial compounds will influence the baby's susceptibility to chronic disease.»

«In the future, such efforts could allow us to much better understand human - microbiome interactions, model malnutrition disorders and inflammatory diseases of the gut, and perform personalized drug testing,» said co-first author Alessio Tovaglieri, a Graduate Student at the Department of Health Science and Technology at ETH Zurich in Switzerland, who performs his thesis work on Ingber's team.

Several other components would be disbursed among the National Institute of General Medical Sciences (such as disease model resources), NIH's imaging institute, and its institute for minority health research.

The discovery means investigators now can grow both parts of the human stomach to study disease, model new treatments and understand human development and health in ways never before possible.

In an article published in The American Journal of Medicine, researchers discuss how existing health care delivery models are poorly constructed to manage chronic disease, and how a reengineering of the health care system might offer some hope in meeting this challenge.

In collaboration with the United States Department of Agriculture (USDA), researchers in the UPV / EHU's «Nutrition and Obesity» Group, which belongs to the Spanish Biomedical Research Centre in Physiopathology of Obesity and Nutrition (CIBERobn) of the Carlos III Institute of Health, have observed in animal models that its administration reduces the build - up of body fat, which could reduce the risk of developing other diseases like diabetes.

Dr. Grover and his colleagues used data from the National Health and Nutrition Examination Survey (from years 2003 to 2010) to develop a model that estimates the annual risk of diabetes and cardiovascular disease in adults with different body weights.

Mathematical models of infectious diseases play an important role in informing public health policy.

Drugs capable of activating silenced genes improve survival and growth outcomes in a mouse model of Prader - Willi syndrome (PWS), a rare and incurable childhood disease, according to a study funded by the National Institutes of Health (NIH).

Making these data publicly available to researchers will build upon the past success of NHGRI's rapid data access model, and will continue to expand our knowledge of human health and disease.»

A new model for post-integration latency in macroglial cells to study HIV - 1 reservoirs of the brain, AIDS, DOI: 10.1097 / QAD.0000000000000691 Link to the original publication As German Research Center for Environmental Health, Helmholtz Zentrum München pursues the goal of developing personalized medical approaches for the prevention and therapy of major common diseases such as diabetes mellitus and lung diseases.

The work recently received a $ 1.7 million National Institutes of Health grant to delve into the mechanisms that occur as the cells reprogram, and to employ the cells for treating the Parkinson's - like symptoms in a mouse model of hypomyelinating disease.

Using this model, individuals and public health officials can monitor disease incidence and implement strategies — such as vaccination campaigns, communicating to the public and allocating resources — to stay one step ahead of infectious disease spread.

Understanding cattle movement patterns as well as the connectivity of the various sectors of the U.S. cattle industry and incorporating these in the models would allow USDA Animal Plant Health Inspection Service (APHIS) Veterinary Services (VS) to develop more effective regulations and control strategies for various animal diseases, including bovine TB.

«What we've shown in the monkey model matches a lot of what people have observed in epidemiological studies of humans,» says Emma Mohr, a pediatric infectious disease fellow at UW — Madison and first author on the study with Matthew Aliota and Dawn Dudley, research scientists in UW — Madison's schools of Veterinary Medicine and Medicine and Public Health, respectively.

BETHESDA, Md., Wed., Oct. 5, 2005 - The National Institutes of Health (NIH) today announced contracts that will give researchers unprecedented access to two private collections of knockout mice, providing valuable models for the study of human disease and laying the groundwork for a public, genome - wide library of knockout mice.

The Cancer, Ageing and Somatic Mutation Programme encompasses three Projects that respectively cover the genomics of human cancers; functional analysis of the cancer genome using a range of in vitro and in vivo model systems; and the characterisation of somatic mutations in development and adult homeostasis in health and disease.

So desirable is the zebrafish as a scientific model that the National Institutes of Health recently launched the NIH Zebrafish Initiative Website, offering funding for studies of cancer, cardiovascular, blood and pulmonary diseases, eye development and disease, gene function, circadian rhythms, aging, longevity, immune system development and function, addiction, hearing, balance, smell and taste.

PHENOMIN's involvement in the IMPC will fulfill a key item of the the National Alliance for life sciences and health (AVIESAN) strategic plan that consists in applying mouse genetics to analyze the mechanisms of disease and to use this knowledge for advancing fundamental research and human health (AVIESAN report on the use and needs of mouse models in the French scientific community, 2010).

Telomere length predicts both cellular health and disease in rodent models and humans.8 Shorter telomeres predict onset of cardiometabolic diseases of aging.9 Chronic stress is associated with higher inflammation, shorter telomeres, and lower activity levels of telomerase, the cellular enzyme that elongates telomeric DNA.10, 11 Levels of amyloid beta (Aβ) proteins circulating in the blood appear to be stress - related in rodent models12 and may be affected by stress reduction, and greater Aβ42 / Aβ40 ratios are associated with lower risk of dementia.13

It is proactive rather than reactive, focuses on the individual patient, emphasizes wellness, and will create a virtual cloud of billions of health data points for each person that can be reduced to simple models about how to optimize wellness and minimize disease.

Moreover, PHENONIM - ICS is involved in European projects presenting a strong impact on human health: Interreg CARDIOGENE (Genetic mechanisms of cardiovascular diseases), GENCODYS (Genetic and epigenetic networks involved in cognitive dysfunctions), AgedBrainSYSBIO (Basic studies of brain aging), as well as projects in partnership with industry: MAGenTA (an Industrial Strategic Innovation project supported by Bpifrance about the treatment of major urogenital diseases) and CanPathPro (H2020 program), to develop a predictive modeling platform of signaling pathways involved in cancers.

The role of αCaMKII autophosphorylation in the establishment of alcohol addiction Alanna Easton, King's College, UK Novel age - dependent learning deficits in a mouse model of Alzheimer's disease: implications for translational research Karienn Montgomery, University of Florida, USA Microsatellite regions upstream of the vole Avpr1a gene contribute to both individual and species differences in receptor expression Zoe Donaldson, Columbia University, USA Per Genes and Addiction Stephanie Perreau - Lenz, Central Institute of Mental Health, Germany

As a model, he pointed to the Women's Health Initiative, a federal study that followed 162,000 women over 15 years to measure the effectiveness of treatments for heart disease, osteoporosis, and cancer.

The researchers hope that their modeling framework helps in the creation of more effective and lower cost public health responses to infectious disease.

Among the newly funded investigations are: the development of animal models of diabetic eye disease to learn how fenofibrate, a drug clinically - approved to treat cholesterol, protects the eye from diabetes - related damage; the development of a specialized camera to capture how the retina's rods and cones (responsible for turning light energy into shapes and colors) work in health and how they fail in retinal diseases; and the exploration of mechanisms by which intestinal tract bacteria impact the health of the eye.

Requests for Single Reprints: Martial L. Ndeffo - Mbah, PhD, Center for Infectious Disease Modeling and Analysis, Yale School of Public Health, 135 College Street, Suite 200, New Haven, CT 06510; e-mail, [email protected].

Be viewed as a model for the integration of the latest knowledge into the provision of health care and disease prevention, and for transferring what we have learned into the community.

Current Author Addresses: Drs. Ndeffo - Mbah and Galvani and Ms. Parpia: Center for Infectious Disease Modeling and Analysis, Yale School of Public Health, 135 College Street, Suite 200, New Haven, CT 06510.

His research focuses on understanding the role of genetic variation in contributing to human health and disease using mouse models of human disease, and more recently exploiting technologies developed for biomedical research for application in the field of genetic pest management.

adapt computer hardware or software for medical science or health care applications (for example, develop expert systems that assist in diagnosing diseases, medical imaging systems, models of different aspects of human physiology or medical data management)

Demonstrate critical thinking of short - term and long - term approaches and patient goals that embrace the integrative and functional medicine model of addressing the root cause of disease, including preventive health care.

However, inherent in the model of the health - illness continuum (as well as in Ayurvedic model) is the idea that disease develops gradually, showing up first as subclinical imbalances.

Naturopathic medicine is a patient - centered model of care that blends the best of modern science and traditional healing wisdom to develop comprehensive treatment plans that not only treat disease but also allow patients to restore optimal health.

The evidence - based training, practical tools, and passionate community you need to move beyond the conventional disease management model of medicine and join the movement to reinvent health care.