Sentences with phrase «healthspan of»

The goal of anti-aging medicine is to use recent scientific advances and treatment modalities to promote «Healthy Aging» and to prolong the healthspan of an individual — so that more of their years are spent in good health and few, if any, are spent with disease.

His project asks a new question that explores the potential benefits of mTOR inhibition as a means of extending healthspan of our skeletal system.

Together these aims will help to decipher the α - DC detoxification network and identify therapeutic targets and novel compounds that can mitigate diabetic complications and extend healthspan of diabetics.

Not exact matches

Any intervention which improves or helps ensure Insulin sensitivity is a great candidate for support of healthspan.

I would monitor my body - weight, composition, cholesterol profile, chronic inflammation indicated by C - Reactive Protein (CRP) and Heart Rate Variability (HRV) whilst doing so to help assess whether the diet was something to consider following periodically or continuously since insulin sensitivity is very important but not the sole factor determining the healthspan supporting virtues of a dietary template.

«This study adds evidence that it will be possible to extend human lifespan and healthspan,» says Brian Kennedy, of the National University of Singapore.

The finding, published in Nature Cell Biology, shows that once disrupted, it takes time for the inflammatory loop to reestablish, providing proof - of - principal that intermittent dosing could provide a way to reap the benefits of rapamycin, an FDA - approved drug that extends lifespan and healthspan in mice, while lessening safety issues associated with its use.

It also aims to elucidate the links between aging, longevity and radioresistance, and the ways in which research into enhancing human radioresistance could synergistically enable human healthspan extension, ultimately highlighting how ongoing research into the very well - funded sphere of aerospace research could galvinate progress in biomedical gerontology, a massively under - funded area of research despite the grave economic burden posed by demographic aging» said Franco Cortese, an author of the paper and Deputy Director of the Biogerontology Research Foundation.

Furthermore, given the massive amount of funding allocated to research into facilitating and optimizing space exploration and optimization, the researchers hope to have shown how research into enhancing radioresistance for space exploration could galvanize progress in human healthspan extension, an area of research that is still massively underfunded despite its potential to prevent the massive economic burden posed by the future healthcare costs associated with demographic aging.

Calorie restriction dramatically extends not only the lifespan of laboratory animals, but also their «healthspan» — how long they live free of disease.

«In theory, any of these factors could be therapeutic targets to extend healthspan.

In particular we are focusing on the impact of diet on intestinal barrier function and the associated innate immune responses to modulate healthspan.

Founded by Paul F. Glenn in 1965, the mission of the Glenn Foundation For Medical Research is to extend the healthy years of life through research on mechanisms of biology that govern normal human aging and its related physiological decline, with the objective of translating research into interventions that will extend healthspan with lifespan.

The overall aim of this project is to examine the role of tissue - specific changes in mRNA translation in response to dietary restriction (DR) and to examine their role in modulating metabolism, muscle activity and healthspan using D. melanogaster.

Based in Novato, CA, the Buck houses 21 independent laboratories and is dedicated to extending «healthspan,» the healthy years of human life by slowing the aging process.

Faculty Henri Jasper, PhD has already extended lifespan and healthspan in fruit flies by enhancing the regenerative capacity of the adult stem cells that line their mid-gut.

«We already know that manipulating mTOR increases both lifespan and healthspan in mice,» said Kennedy, who added that some of the mice will be treated with drugs that inhibit mTOR.

UNITY Biotechnology Launches with a Focus on Preventing and Reversing Diseases of Aging February 03, 2016 SAN FRANCISCO --(BUSINESS WIRE)-- UNITY Biotechnology today announced that it is developing medicines to treat and eliminate age - related diseases and increase healthspan, or the amount of time an individual lives in good health.

«Exercise also creates ketone bodies — that may be one of the mechanisms why it shows such protective effects on brain function and on healthspan and lifespan,» he said.

Dietary restriction and the modulation of nutrient - sensing pathways are robust and reproducible interventions that extend life / healthspan in model organisms.

The author interviewed some naysayers on the topic of healthspan, but ultimately I think it's clear that if Silicon Valley can figure out how to increase human health, that is a

Greater attention to behavioral outcomes is critical for aging research's ultimate goal of increasing not only lifespan but healthspan, the period over which the quality of life remains high.

These data indicate that cellular senescence is causally implicated in generating age - related phenotypes and that removal of senescent cells can prevent or delay tissue dysfunction and extend healthspan.

The research is aimed at determining whether the reduced gene expression promotes healthspan and delays the onset of age - related diseases in the mice.

Sponsored by the Glenn Foundation for Medical Research in collaboration with AFAR, the two - year, $ 200,000 BIG award is designed to provide timely support to a small number of research projects that are building on early discoveries that show translational potential for clinically relevant strategies, treatments and therapeutics that address human aging and healthspan.

Our study may implicate haploinsufficiency of protein - coding genes as a general mechanism of aging of the hematopoietic system and of aging - associated disorders more generally and provide new insights into the genetics of aging and healthspan.

The extension of life may not represent a significant number of years lived but rather an improved quality of life or healthspan.»

USC's Dr. Valter Longo has created the Fast Mimicking Diet, a five day partial eating diet that in research decreased risk factors / biomarkers for aging, diabetes, cardiovascular disease, and cancer without major adverse effects, providing support for the use of FMDs to promote healthspan.

She received her BS in Exercise Biology and MSc in Nutritional Biology at UC Davis where her research focused on the effects of low carbohydrate and ketogenic diets on longevity and healthspan in mice.

4) focus on the diets of remaining hunter gatherers pushed into extreme environments, whereas several contemporary African savannah & forest hunter gatherers eat predominantly plant - based; 5) the unfounded assumption that the same diet that maximizes growth in youth will also maximize healthspan free of chronic disease, which experimental gerontology has resoundingly dismissed.

Seems like colored grains are biochemically plausible, inexpensive sources of CD38 - inhibiting anthocyanins for increasing cellular [NAD +], activating Sirt1, and improving healthspan.

I'm constantly monitoring the science on extending healthspan and if something better comes along or one of my current practices is proven flawed I'll happily update my plans and let you all know.

Lower than typical blood glucose is found in almost all models of extended lifespan (and healthspan) including caloric restriction and centenarians.

Spermidine both increases lifespan and healthspan in animal models, and is enriched in the blood of humans living past 90.

The symptoms of fast aging, from fatigue to osteoporosis to cancer, can lead to a shorter healthspan (the amount of time you feel most alive and brimming with energy).

Discover Shamanic Energy Medicine, a system founded on the experience of Oneness that restores your inner harmony and can make your healthspan equal your lifespan.

Extend your dog's healthspan by testing for genetic diseases that occur later in life including glaucoma, degenerative myelopathy, and dilated cardiomyopathy, three of the most common adult onset diseases in dogs.

The genetic age that we report is an estimation of where your dog is in his or her healthspan.

«Many pet owners may not be aware of the changes that happen to their pets as they age or that nutrition can have a positive impact on their healthspan, the period of life spent in good health.»