Sentences with phrase «healthy brain samples»

The researchers analyzed eight Alzheimer's and six healthy brain samples from a brain bank, where people donate their brains after death for medical research.

Not exact matches

The researchers detected this SMN long noncoding RNA, or lnc - RNA (pronounced «link RNA») for short, in human embryonic kidney cells, brain cell samples and neurons derived from the stem cells of healthy people and those with spinal muscular atrophy type I and II.

Ronald Kahn and his colleagues at Harvard Medical School in Boston compared gene expression in brain samples from mice with type 1 or type 2 diabetes against those of healthy mice.

The researchers tested samples of brain cells from people with MS and healthy control subjects and found evidence of the virus in the olfactory bulb in both groups.

In comparison to RNA from healthy brains, more of the RNA from Alzheimer's brain samples was unspliced.

The study divides 177 blood and 27 post-mortem brain samples into several groups, establishing that careful analysis of RNA transcripts in blood samples has the ability to distinguish early clinical AD, Parkinson's disease (PD), and cognitively healthy patients.

Then tissue samples were collected from brain areas where healthy neurons had been introduced.

The Raman images now show protein activity at neural cell level, but the sensitivity is high enough for detecting areas that are even smaller — as is the case with the brain sample of the healthy person.

Recent studies have found elevated levels of this protein in post-mortem brain samples of patients with MS.. In this latest work, investigators compared the frequencies of «more active» and «less active» variants of the DNA sequences that control expression of the galanin gene between healthy controls and MS patients.

They used state - of - the - art DNA sequencing technology to screen for retrotransposons in tissue samples taken postmortem from three individuals who were healthy when alive and had no neurological disease or signs of abnormality in their brain tissue.

Behavior Cardiology - Heart Dentistry and Oral Surgery - Teeth / Mouth Genetics - Sample Collection Only Internal Medicine - Lung and Gastrointestinal Disorders, Hormone Imbalances, Infectious Diseases (etc.) Neurology and Neurosurgery - Brain / Nerves Nutrition Oncology - Cancer Ophthalmology - Eyes Orthopedic Surgery and Lameness - Bones / Joints Soft Tissue Surgery Theriogenology - Reproduction Healthy Animals

Bio-behavioral Markers of Bipolar Conversion Currently enrolling healthy control young adults 18 - 25 years old.This study (< 6 hours) involves interviews, IQ tests, special computer games, genetic sample, and MRI brain scan.For all studies, participants are compensated for their time.

Studies were included in our meta - analyses if the following criteria were given: (I) included at least one clinical group with described aggressive behaviour, (II) in combination with a healthy control sample, (III) conducted during adolescence, (IV) reported whole brain gray matter volume alterations or whole brain functional neuroimaging data, (V) results are described using a standard reference space (Talairach or MNI) and (VI) the same threshold was used throughout the whole brain analysis.

Given their typical age of onset, a broad range of mental disorders are increasingly being understood as the result of aberrations of developmental processes that normally occur in the adolescent brain.4 — 6 Executive functioning, and its neurobiological substrate, the prefrontal cortex, matures during adolescence.5 The relatively late maturation of executive functioning is adaptive in most cases, underpinning characteristic adolescent behaviours such as social interaction, risk taking and sensation seeking which promote successful adult development and independence.6 However, in some cases it appears that the delayed maturation of prefrontal regulatory regions leads to the development of mental illness, with neurobiological studies indicating a broad deficit in executive functioning which precedes and underpins a range of psychopathology.7 A recent meta - analysis of neuroimaging studies focusing on a range of psychotic and non-psychotic mental illnesses found that grey matter loss in the dorsal anterior cingulate, and left and right insula, was common across diagnoses.8 In a healthy sample, this study also demonstrated that lower grey matter in these regions was found to be associated with deficits in executive functioning performance.

Understanding brain — behavior relationships in psychiatrically healthy samples, especially early in development, will help inform normative developmental trajectories and neural alterations in depression and other affective pathology.