Not exact matches
Liver failure occurs when
healthy cells called
hepatocytes are damaged by alcohol and disease.
Eliminating these constraints,
hepatocytes differentiated from human induced pluripotent stem (hiPS) cells provide an unlimited supply of functional
hepatocytes from each parental cell line, which can be derived noninvasively from a diseased or
healthy person.
The researchers found that patients from MODY3 families had one of several different mutations in the gene for
hepatocyte nuclear factor 1 alpha (HNF -1-alpha) but
healthy subjects had normal copies of the gene.