Not exact matches
In addition to looking at mouse models of diabetes, the researchers also showed that exposure of human pancreatic
islet cells — both from
healthy donors and from patients with Type 1 diabetes — to fasting - mimicking diet in a dish stimulated insulin production.
Melton began to study how stem
cells turn into either
healthy or unhealthy
islet cells.
We got
islet cells from the pancreases of
healthy dogs, encapsulated them, and transferred them to diabetic dogs, who became insulin independent.
Image of non-diabetic
healthy human
islet cells that reside in pancreas.
If we could find therapies that detect complications at an early stage, people with diabetes could lead
healthier, more productive lives,» says senior author Rohit Kulkarni, M.D., Ph.D., Principal Investigator in the Section on
Islet Cell and Regenerative Biology at Joslin Diabetes Center and Associate Professor of Medicine at Harvard Medical School.
To create a lasting source of insulin - producing beta
cells for transplant, we are developing new methods to promote differentiation from pancreatic stem
cells into
healthy islets.
Patients with Type - 1 diabetes don't have enough
healthy islets of Langerhans
cells — hormone - secreting
cells of the pancreas.