Sentences with phrase «healthy study volunteers»

However, it has also been shown to induce symptoms of psychosis among healthy study volunteers and is thought to be a risk factor in developing psychosis.

Not exact matches

In contrast, positive expectations of treatment doubled the natural physiological or biochemical effect of the opioid drug among the healthy volunteers in the study.

According to Dr Lustig: «The thing that's important about that study is that the [volunteers] were [on] a healthy low carb diet and a healthy low fat diet.

In a study at the University of the Philippines, researchers used a randomized cross-over design to compare the effects on blood glucose of brown rice and white rice on 10 healthy and nine Type 2 diabetic volunteers.

Five healthy nonsmokers (2 men and 3 women; age: 41 — 70 y; BMI: 22 — 29) were recruited as study volunteers.

The agency insisted that safety studies be completed first on 18 healthy volunteers to ensure that the drug didn't trigger damaging side effects.

Led by neurologist Bradley Schlaggar, the group studied 238 healthy volunteers, 7 to 30 years old, using functional MRI, a technique that identifies active neural circuits based on blood flow and blood oxygen levels.

The study compared 20 patients hospitalized for surgery of chronic subdural hematoma — a serious form of intracranial bleeding — with 20 healthy volunteers.

The study examined the effects of smoking on various biochemical processes in the blood and vessels of 20 healthy non-smokers who volunteered to smoke three cigarettes.

In the largest study of its kind, researchers found only 34 (0.31 %) healthy volunteers with serious adverse events, which are defined by the FDA as those that result in death; are life - threatening; require or prolong in - patient hospitalization; or cause a disability, congenital anomaly or birth defect.

In this study, 50 patients and six healthy volunteers at Queen Elizabeth Hospital in Birmingham and Royal Infirmary of Edinburgh underwent digital image scanning, and the results were processed by clinical and imaging specialists.

«It is quite encouraging that lexaptepid helped maintain appropriate levels of iron in the bloodstream of healthy volunteers without compromising the immune response,» said lead study author Lucas van Eijk, MD, of Radboud University Medical Center in Nijmegen, Netherlands.

Another study found that healthy volunteers sitting in a hospital had a higher pain threshold and better pain tolerance when they were watching a video of nature scenery than when they were watching a blank static screen.

A 2009 study by Harvard University researchers showed that in just 10 days, three of eight healthy volunteers developed prediabetic blood - sugar levels when their sleep - wake schedule was gradually shifted out of alignment.

Beall and her co-workers studied 88 healthy volunteers from the Tibetan district of Panam Xiang, where the elevation is 4200 meters.

To do this, the research team enrolled 65 healthy volunteers aged 18 to 50 years in the human challenge study — a type of research study in which individuals are exposed to disease - causing pathogens under carefully controlled conditions.

It also has similar side effects — like excitability, nervousness, and good mood.THE FINDINGS 36 healthy, well - educated, psychologically stable middle - aged adults who had never used hallucinogens volunteered for the study.

During the study, healthy volunteers were exposed to experimental hypoglycemia.

The tolerability profile in patients with advanced cancer was similar to that observed in two previous studies in 150 healthy volunteers who received entolimod in a similar dose range.

Between 2000 and 2003, he and his colleagues had collected detailed data on the sleep patterns of 33 healthy volunteers for an unrelated study on the effects of aging on sleep.

A study led by Dr Ben Nicholas, of the University of Southampton, and published in the Journal of Allergy and Clinical Immunology, assessed lung samples from asthmatics and healthy volunteers.

The European research collaboration behind this study focuses on deep immunological analysis of the immunogenicity and reactogenicity of the Ebola vaccine in healthy volunteers.

The rule provides a framework for potential licensure of medical products when definitive efficacy studies that would involve exposing healthy human volunteers are unethical and field trials after accidental human exposure are not feasible.

This study tested nasal naloxone at 1 mg, 2 mg, and 4 mg doses on 38 healthy volunteers, compared with 0.4 mg IM and 0.4 mg intravenous doses.

Just a few weeks ago, WHO said that using any of the experimental drugs or vaccines in the pipeline simply wasn't in the cards, because none of them have been through a phase I clinical study, the type of trial in which medical products are tested on healthy volunteers to study their toxicity.

Markus Zeitlinger from the Department of Clinical Pharmacology and Werner Dolak from the Department of Medicine III studied sixty healthy volunteers over a period of fourteen days, monitoring the drug - related reaction in the intestinal tract by means of capsule endoscopy imaging.

The study — conducted in collaboration with the Santa Maria della Misericordia University Hospital in Udine, under the leadership of Raffella Rumiati, in charge of SISSA neuroscience and society lab — has involved 18 Parkinsonian patients who underwent deep brain stimulation and 18 healthy volunteers.

Case No. 18 states that a study in which a healthy volunteer undergoes MRI brain imaging while performing a working memory test is now a clinical trial because the effect being evaluated — brain function — is a health - related outcome.

Concerns arose this summer when an NIH official said the definition could apply to many basic behavioral research projects, including brain studies — for example, having healthy volunteers perform a computer task while wearing an electrode cap or lying in an MRI machine.

This study included 13 patients with prostate cancer (four newly diagnosed and nine post-therapy) and five healthy volunteers.

Researchers studied almost 2,000 healthy women volunteers from TwinsUK who had completed a food questionnaire designed to estimate total dietary flavonoid intake as well as intakes from six flavonoid subclasses.

«These results enable us to determine whether potential treatments will be effective against patients» symptoms by testing them first in healthy volunteers and defining the best doses based on objective physiological data before conducting costly clinical trials,» said Jeffrey Lieberman, MD, the Lawrence C. Kolb Professor and Chairman of the Department of Psychiatry at CUMC, and Principal Investigator of this study.

As reported in a Researcher Letter, the study included 14 healthy, unacclimatized volunteers (7 male and 7 female participants, average age, 35 years) who were studied at baseline (1,119 feet), after ascent to 14,957 feet within 24 hours, and more than 14 days after return by fluorescein angiography.

She is also careful to point out that the two drugs — administered only to healthy volunteers in the study — are likely to have different effects on social behavior in people taking them to treat an illness.

In 1997, he studied the effects of gently stimulating the frontal eye fields of six healthy volunteers.

Preliminary studies in patients and healthy volunteers suggest substantial and sustained positive effects.

The study recruited 288 participants in Edinburgh, including stroke and lupus patients and healthy working age volunteers.

It also demonstrates the value of using healthy volunteers in studies carried out at high altitude to patients at sea level.

In the study, Cohen and his team measured the telomere lengths of white blood cells from 152 healthy volunteers between the ages of 18 and 55.

According to Tomas Cihlar, Ph.D., of Gilead Sciences, the company is currently conducting phase I clinical studies of the compound in healthy human volunteers to establish the safety and pharmacokinetic profile.

Researchers from the Perelman School of Medicine at the University of Pennsylvania instead studied six healthy young male volunteers to collect physiological information as they went about their normal daily lives.

At study entry, serum transthyretin levels were modestly lower in patients with transthyretin amyloidosis than in healthy volunteers, a finding that was consistent with reports showing lower transthyretin levels in patients with transthyretin amyloidosis than in either asymptomatic disease carriers or healthy controls.36

All participants in the ALN - TTR02 trial were male, since the protocol excluded women with childbearing potential in this early - phase study involving healthy volunteers.

We have more than 300 treatment trials or healthy volunteer studies currently open.

Already approved by the hospital's IRB, the study had more than two dozen healthy volunteers standing by.

Study volunteers were screened carefully to confirm they were healthy and did not have symptoms of acute infection.

Moderna's Zika mRNA vaccine, mRNA - 1325, is currently in Phase 1/2 clinical study in healthy volunteers.

We are also looking for children to volunteer as healthy control subjects for this study.

The test integrates data from discovery and replication studies published in major peer - reviewed journals and involving nearly 100,000 breast cancer patients and healthy volunteers from many populations, principally of European descent.

To test whether oral E4 lowers testosterone levels, Dutman and her colleagues conducted a double - blind, randomized, placebo - controlled study in 45 healthy male volunteers between 40 and 70 years of age at one medical center.