Not exact matches
Researchers from the Eaton - Peabody Laboratories of the Massachusetts Eye and Ear and Harvard Medical School have created a new
mouse model
in which by expressing a gene
in the inner ear hair cells — the sensory cells that detect sound and sense balance — protects the
mice from
age - related
hearing loss (ARHL) and noise - induced
hearing loss (NIHL), the two most common forms of deafness.
«To our knowledge, our model is the first
in which expression of a single gene
in postnatal hair cells results
in hair cell survival and
hearing preservation
in mice that otherwise suffer from
age - related and noise - induced
hearing loss,» Dr. Chen said.
But by the
age of 80 - 90 days, untreated USH3
mice in the study couldn't
hear 100 decibels — akin to standing next to a running snowmobile or
in a busy woodshop and not
hearing anything.
the presence of this mitochondrial sequence polymorphism
in mice homozygous for the ahl allele results
in age related
hearing loss by 3 months of
age, which is absent when the CAST / Ei mitochondrial sequence is instead present
Yet another primary interest is
in the genetics of
hearing and deafness disorders using
mouse models of human deafness disorders and genome - wide association studies
in age - related
hearing impairment.
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