Sentences with phrase «heart cell interactions»
It also provides novel insight into human mesenchymal stem cell - heart cell interactions that can guide future experimental studies to understand the mechanisms underlying mesenchymal stem cell therapy for the heart.
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«Cardiac stem cells from heart disease patients may be harmful: Researchers discover molecular pathway involved in toxic interaction between host cells and immune system.»
Researchers, led by Joshua Mayourian at the Icahn School of Medicine at Mount Sinai, used mathematical modeling to simulate electrical interactions between these stem cells and heart cells to develop insight into possible adverse effects, as well as to hypothesize new methods for reducing some potential risks of this therapy.
Biologists, physicists, mathematicians, and computer scientists have begun cooperating on a sophisticated «systems biology» aimed at understanding how the countless molecular interactions at the heart of life fit together in the workings of cells, organs, and whole animals.
Molecular analysis showed that heart cells in affected animals were poorly developed and had mitochondrial defects, indicating that Sap130 - Pcdha9 gene interactions play a crucial role not only in heart development but also in regulating metabolic function of the cardiac muscle.
So say researchers in Lisbon, Portugal, who have used the technique to show that the interactions between a protein known as fibrinogen and erythrocytes (red blood cells) are modified in people with chronic heart failure.
Critical transitions across states and tipping points lay at the heart of most complex problems in modern biology, including reversible physiological adaptation to environmental change, evolution of interactions in the microbial loop, development of an adult body plan from an embryo, differentiation of a stem cell, and transition from health to disease.
To replicate the cell interactions in the developing heart, the scientists developed a novel method of growing two distinct cell types together.
«Not only are these transcription factors vital for turning on certain genes, but their interaction is important to keep each other from going to the wrong place and turning on a set of genes that doesn't belong in a heart cell.»