When they killed the animals a week later, they found that the virus had broken apart dystrophin in their hearts and that the membranes of
heart cells infected with Coxsackie B virus were more permeable to blue dye than uninfected cells.
Not exact matches
Coxsackie B virus (red)
infects cells positive for the
heart stem
cell marker Sca - 1 (green).
To test whether the childhood infection and stem
cell depletion had any effect on the adult
heart, the researchers exposed
infected mice to two different types of cardiac stress.
After cultured rat
heart cells were
infected with the Coxsackie B virus, the amount of normal dystrophin declined within 3 days.
Most
infected puppies required extraordinary and expensive medical care to survive, and very young puppies rarely did, as the virus
infected the rapidly dividing
cells of the
heart.
Parvovirus also attacks the white blood
cells, and when young animals are
infected, the virus can damage the
heart muscle and cause lifelong cardiac problem (pets.webmd.com)
Spread through contact with
infected feces, the long - lived virus attacked rapidly reproducing
cells such as those lining the gastrointestinal tract, bone marrow, lymph nodes, and
heart.