Sentences with phrase «heart ejection fraction»

The control group did not experience the same increase in heart ejection fraction.

Not exact matches

The TOPCAT trial is the first randomized, double - blind trial to assess the effect of spironolactone on clinical outcomes in these patients with heart failure and preserved ejection fraction.

The rationale for using spironolactone - an inexpensive, generic, medication - stems from the pioneering research of Bertram Pitt, MD, University of Michigan School of Medicine, who showed the benefit of this class of drugs in patients with heart failure and reduced ejection fraction, and who also served as chair of the TOPCAT Steering Committee.

A late - breaking clinical trial, known as the Treatment of Preserved Cardiac Function Heart Failure with an Aldosterone Antagonist (TOPCAT) trial, to be presented at the American Heart Association (AHA) Scientific Sessions, November 18, 2013, demonstrates that spironolactone did not reduce the primary outcome of cardiovascular death, heart failure hospitalization, nor surviving a cardiac arrest in patients with heart failure and preserved ejection fraction (pump functHeart Failure with an Aldosterone Antagonist (TOPCAT) trial, to be presented at the American Heart Association (AHA) Scientific Sessions, November 18, 2013, demonstrates that spironolactone did not reduce the primary outcome of cardiovascular death, heart failure hospitalization, nor surviving a cardiac arrest in patients with heart failure and preserved ejection fraction (pump functHeart Association (AHA) Scientific Sessions, November 18, 2013, demonstrates that spironolactone did not reduce the primary outcome of cardiovascular death, heart failure hospitalization, nor surviving a cardiac arrest in patients with heart failure and preserved ejection fraction (pump functheart failure hospitalization, nor surviving a cardiac arrest in patients with heart failure and preserved ejection fraction (pump functheart failure and preserved ejection fraction (pump function).

Ultrasound studies of the macaques» hearts showed that the ejection fraction, an indication of the hearts ability to pump blood, improved in some of the treated animals but not all.

The standard test for risk assessment in relation to life - threatening cardiac rhythm disturbances is currently the left ventricular ejection fraction, which represents a measure of the heart's function and measures the volume of the beat in relation to the overall volume of blood in the ventricle.

Findings from the Treatment of Preserved Cardiac Function Heart Failure with an Aldosterone Antagonist (TOPCAT) trial, have revealed that adding the medication known as spironolactone (Aldactone) to existing therapy did not significantly reduce the composite time to either death from cardiovascular causes, surviving a cardiac arrest, or hospitalization to manage heart failure in patients with heart failure and a preserved ejection fraction in a study funded by the National Heart, Lung and Blood Institute, National Institutes of HeHeart Failure with an Aldosterone Antagonist (TOPCAT) trial, have revealed that adding the medication known as spironolactone (Aldactone) to existing therapy did not significantly reduce the composite time to either death from cardiovascular causes, surviving a cardiac arrest, or hospitalization to manage heart failure in patients with heart failure and a preserved ejection fraction in a study funded by the National Heart, Lung and Blood Institute, National Institutes of Heheart failure in patients with heart failure and a preserved ejection fraction in a study funded by the National Heart, Lung and Blood Institute, National Institutes of Heheart failure and a preserved ejection fraction in a study funded by the National Heart, Lung and Blood Institute, National Institutes of HeHeart, Lung and Blood Institute, National Institutes of Health.

Iron deficiency is present in approximately 50 percent of patients with heart failure with reduced left ventricular ejection fraction (HFrEF; ejection fraction: a measure of how well the left ventricle of the heart pumps with each contraction) and is associated with reduced functional capacity, poorer quality of life, and increased mortality.

In patients with the implantable device, the heart got smaller, the left ventricular diastolic volume decreased significantly and the heart became stronger, with significant improvements in left ventricular ejection fraction.

«There currently are no existing therapies to address the prognoses of the approximately 40 percent of patients with heart failure and a preserved ejection fraction,» said Eldrin Lewis, MD, advanced heart failure specialist, Brigham and Women's Hospital (BWH) Division of Cardiovascular Medicine, Department of Medicine, study co-author.

Participants with symptomatic heart failure and a left ventricular ejection fraction of 45 percent or more (normal or near normal contractions) were randomized to receive either spironolactone (15 to 45 milligrams daily) or matching placebo, and were followed for an average of nearly 3.3 years.

Contrary to popular practice, a measure of the heart's pumping function known as «left ventricular ejection fraction» is not associated with the long - term outcomes of hospitalized heart failure patients, a UCLA - led study of Medicare patients has found.

Hospitalized heart failure patients in all age groups within the study and with all levels of ejection fraction had significantly lower rates of survival after five years and a higher risk of re-hospitalization than people in the United States without heart failure.

This is the first study to use national data to specifically categorize heart failure by three distinct ejection fraction subgroups.

Although the primary endpoint was not met, a statistically significant 4 percent improvement was seen in a secondary endpoint, left ventricular ejection fraction — a measure of how much blood is being pumped out of the left ventricle — in patients whose STEMIs involved the front wall of the left ventricle (the heart's main pumping chamber), he said.

A new study by researchers at Boston University School of Medicine (BUSM) and Boston Medical Center (BMC) found comparable long - term outcomes between congestive heart failure patients with preserved ejection fraction commonly known as «diastolic heart failure» and congestive heart failure with reduced ejection fraction also known as «systolic heart failure.»

The 10 - year Warfarin and Aspirin for Reduced Cardiac Ejection Fraction (WARCEF) trial is the largest randomized, double - blind comparison of aspirin and warfarin (also known by its brand name Coumadin) for heart failure, following 2,305 heart failure patients whose heart muscle pumps less oxygen - rich blood into the body, known as reduced ejection fraction, at 168 study sites in 11 countries on three conEjection Fraction (WARCEF) trial is the largest randomized, double - blind comparison of aspirin and warfarin (also known by its brand name Coumadin) for heart failure, following 2,305 heart failure patients whose heart muscle pumps less oxygen - rich blood into the body, known as reduced ejection fraction, at 168 study sites in 11 countries on three conFraction (WARCEF) trial is the largest randomized, double - blind comparison of aspirin and warfarin (also known by its brand name Coumadin) for heart failure, following 2,305 heart failure patients whose heart muscle pumps less oxygen - rich blood into the body, known as reduced ejection fraction, at 168 study sites in 11 countries on three conejection fraction, at 168 study sites in 11 countries on three confraction, at 168 study sites in 11 countries on three continents.

Patients treated with processed autologous adipose - derived regenerative cells (ADRCs) injected into the heart muscle demonstrated symptomatic improvement and a trend towards lower rates of heart failure hospitalizations and angina, despite no improvement in left ventricle ejection fraction (LVEF) or ventricular volumes.

Non-Ischemic Heart Failure With Reduced Ejection Fraction Is Associated With Altered Intestinal Microbiota — Themistoklis Katsimichas — Circulation Journal

Non-Ischemic Heart Failure With Reduced Ejection Fraction Is Associated With Altered Intestinal Microbiota

A large - scale metaanalysis on heart failure, using a huge individual patient dataset, found that diabetes was more frequent in women than men, including patients with both reduced and preserved ejection fraction (307).

The average starting ejection fraction was 34 percent, a sign of severe injury to the heart.

Omecamtiv mecarbil is a selective, small - molecule currently being studied in a Phase 3 clinical trial of ~ 8000 patients as a potential treatment for heart failure with reduced ejection fraction in collaboration with Amgen and in partnership with Servier.

Recovery and outcomes were assessed in several ways: MACE (major adverse cardiac events, ranging from hospitalization for chest pain to death), ejection fraction, measured by magnetic resonance imaging, and perfusion or blood flow in the heart, measured by SPECT imaging.

In fact, a previous study led by the same researcher (Mozaffarian, Am J Cardiol 2006 Jan) found that while eating baked or broiled fish was linked to a slower but more powerful heart beat and lower blood pressure, eating fried fish was associated with heart muscle motion abnormalities, a reduced ejection fraction, lower cardiac output, and higher blood pressure.

There are several published studies on Heart Failure patients from mild to severe that see improvement in life expectancy, quality of life, and also improved ejection fraction output.

His team is now studying patients who have especially high risk of heart failure with preserved ejection fraction (HFpEF).

Researchers (Y Omori, T Ohtani, et al), at the Department of Cardiovascular Medicine, Osaka University Graduate School of Medicine, Japan, developed an animal study to analyze potential new treatments for heart failure — specifically heart failure with preserved ejection fraction (HFpEF) in hypertensive heart disease.

The researchers were aware that prognosis of heart failure with preserved ejection fraction is poor.

They will actually impede ejection fraction that is a measure of the ability of your heart to pump blood.

We've gotten our nice randomized study in very sick congestive heart failure patients with low ejection fractions is the V - 4 engine are probiotic use it was actually saccharomyces boulardii and it wasn't that much, about three million.

• increased left ventricular ejection fraction (11, 12) • improved exercise tolerance (12, 13, 14) • increased cardiac output (15) • better prognosis for patients with chronic heart failure (16) • lowered markers of oxidative stress (17, 18)

The key to a traditional policy approval will be a recent echocardiogram, treadmill stress test, or cardiac catheterization showing that the heart is not overly enlarged, and the left ventricular ejection fraction (LVEF) is still within acceptable levels.

Posted in business life insurance, CEO life insurance, coronary artery disease (CAD), heart attack, heart disease, insurance, last minute life insurance, life insurance, life insurance approval Tagged business life insurance, ceo life insurance, chronic CAD life insurance, ejection fraction, family history of CAD, insurance, life insurance, life insurance 6 months aftter stent placement, life insurance 6 - 12 months after heart attack, life insurance post heart attack, post CAD event life insurance, post cardiac event workup

Posted in coronary artery disease (CAD), ejection fraction, heart disease, insurance, life insurance, LVEF Tagged cardiologist normal is normal, echocardiogram, ejection fraction, insurance, life insurance, life insurance underwriter, lipid panel to die for, LVEF, medical test result normal, medical test result not normal enough, mistake that higher EF is better, no actuarial basis, normal range 50 % to 65 %, treadmill stress test, underwriter low normal is almost not normal, underwriters playing doctor