Sentences with phrase «heart tissue»

"Heart tissue" refers to the specific type of cells and structures that make up the heart. It is the special material that forms the walls and inner workings of the heart. Full definition
Experts say that sort of heart tissue injury can lead to higher risk of short - and long - term mortality.
MRI measured the mass of damaged heart tissue in all patients.
Furthermore, in heart tissue from these mice, the scientists found genes turned on that are normally seen in skeletal muscle, not heart muscle.
Scientists have developed an easier, cheaper, and more efficient system for creating three - dimensional human heart tissue from stem cells.
They tested human heart tissue and brain cells, as well as other cell types.
For the moment, the team believe the technology could be used to grow artificial heart tissue for screening new drugs to regulate heart activity.
The researchers pointed out that while this study focused on heart tissue, there is great potential for use of this technology to study other organ development.
If they come back positive, it's an indication the immune system is attacking heart tissue.
Additionally, researchers found that nearly 300 genes showed variation in their expression in heart tissue over the course of a day — a possible basis for the tissue's change in behavior.
The scientist tested their set - up using frozen human skin cells, segments of pig heart tissue, and sections of pig arteries in volumes almost 20 times larger than previously attempted samples.
The technique also lets researchers compare waves moving through heart tissue against waves in other tissues or groups of cells.
Additionally, the researchers report online today in Cell, old mice injected with this protein for 30 days developed younger, stronger heart tissue.
Those cells would naturally grow together to form heart tissue.
For many years, scientists worldwide have been searching for ways to stimulate the regeneration of damaged heart tissue.
These wires are used to deliver energy or heat that destroys the areas of heart tissue that cause the abnormal heart rhythm.
If these come back positive it's an indication the immune system is attacking heart tissue.
But according to a report published today in the early online edition of the Proceedings of the National Academy of Sciences, a strain of laboratory mice dubbed MRL mice succeeded in regenerating heart tissue without the aid of drugs or other treatments.
Dr. Voot Yin talks about how research on the common aquarium fish, the zebrafish, may lead to a drug to regenerate healthy heart tissue after a heart attack.
Neocardiogenic substances are able to stimulate the formation of cardiac progenitor cells which can differentiate into healthy heart tissue, and they include the following:
The tiny fish can regrow fins and even repair damaged heart tissue with genes called fibroblast growth factors and neuregulin 1, respectively.
ab16669 staining rat infarcted heart tissue by Immunohistochemistry (Formalin / PFA - fixed paraffin - embedded sections).
Zebrafish regenerate new heart tissue after injury.
For example, director of the Gladstone Institute of Cardiovascular Disease, Deepak Srivastava, MD, believes the day is near when he could use cellular reprogramming to treat heart disease by converting damaged heart tissue into beating heart muscle cells after a heart attack.
In the case of the obese mice, Sinclair observes, resveratrol increased insulin levels while decreasing glucose levels, resulting in healthier liver and heart tissue when compared with obese mice that did not receive treatment.
«The time is coming when we'll repair heart tissue after a heart attack and restore blood flow to limbs that would otherwise be amputated,» says stem cell researcher Robert Lanza of Advanced Cell Technology in Massachusetts.
Because humans have a limited capacity for heart tissue regeneration, damaged heart muscle is normally replaced with a nonfunctional scar.
The researchers isolated heart tissue samples from a subgroup of 30 patients from the randomized controlled trial.
ab16056 staining COX IV in Mouse heart tissue sections by Immunohistochemistry (IHC - P - paraformaldehyde - fixed, paraffin - embedded sections).
The researchers are using the zebrafish to study how heart tissue regenerates because the fish have what they called an «amazing capacity» to regenerate the form and function of almost any of their body parts.
But the theory remained controversial because heart tissue does not have a-Klotho, which must be present if FGF23 is to signal.
Dr. Bruce Conklin and colleagues from Gladstone and UC Berkeley grew beating heart tissue from stem cells, creating a model of early human heart development.
For the study, the team activated AMPK signaling with drugs that have been used medically to protect heart tissue during surgery and in sports to enhance performance because of its blood flow boosting abilities.
Cardiac cell therapy helps restore blood flow and repair damaged heart tissue without the risk of rejection.
The study team examined heart tissue removed from patients undergoing ventricular implants and found that G6P can cause significant damage to the heart muscle.
When heart tissue becomes stretched through disease, such as congestive heart failure, trouble ensues.
A * STAR researchers and colleagues have developed a method to isolate and expand human heart stem cells, also known as cardiac progenitor cells, which could have great potential for repairing injured heart tissue.
«Micro heart muscle created from stem cells: New technique offers cheaper, faster method to create heart tissue for testing drugs and modeling disease.»
Microscopic image of a piece of rat heart tissue in which the proteins involved in contraction are stained in white, the cell membranes in yellow and nuclei in blue.
In one study, rats on a long - term intermittent fasting diet ended up with increased blood glucose and, in another, rats developed stiffened heart tissue which made it much harder for the heart to successfully pump blood around the body.
The DMC - cultured heart tissue was placed in BSK and back to in vitro culture for 1 week.
Deepak Srivastava and his team at the Gladstone Institute of Cardiovascular Disease in San Francisco created mouse cardiomyocytes by exposing mouse fibroblasts to three transcription factor proteins that activate genes needed for the formation of embryonic heart tissue.
York U chemistry Professor Muhammad Yousaf and his team of grad students have devised a way to stick three different types of cardiac cells together, like Velcro, to make heart tissue that beats as one.
Marbán, like many, believes the improvements came about because transplanted cells secreted chemicals that boosted heart function — not because any new heart tissue grew.
ab16056 staining COX IV in Mouse heart tissue sections by Immunohistochemistry (IHC - Fr - frozen sections).
Okyanos cardiac cell therapy targets the restoration of blood flow to the heart and repairs damaged heart tissue caused by heart attack or ischemic and non-ischemic heart disease.
Through «heart - on - a-chip» technology — modeling a human heart on an engineered chip and measuring the effects of compound exposure on functions of heart tissue using microelectrodes — Lawrence Livermore National Laboratory (LLNL) researchers hope to decrease the time needed for new drug trials and ensure potentially lifesaving drugs are safe and effective while reducing the need for human and animal testing.
Since heart tissue is also composed of collagen, our bio-piezoelectric nanogenerator is expected to be very compatible with the heart.»
«MRI is a unique tool for studying heart tissue that enables us to explore in exquisite detail heart function, necrosis, the state of the microcirculation, and many other parameters that are critical in determining the post-infarction status of the myocardium,» says Dr. Fuster.
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