Sentences with phrase «helped model the disease»
Using data from 23 sites, Winifred Frick, an ecologist at Boston University, helped model the disease's impact on little brown bats.
http://discovermagazine.com/ Not exact matches
Creating and maintaining a healthy lifestyle that you stick to beyond the birth will also make you a model of healthy living for your child, helping him / her to avoid obesity, diabetes, heart disease and other conditions for a lifetime.
They hope to create a human model that could help speed up the development of new drugs and vaccines against the disease, which sickens millions of people and kills thousands each year.
Their mathematical model also predicted how the Disneyland outbreak helped push California back from the tipping point by making parents more afraid of the disease than the vaccine.
In addition to helping understand disease by providing more powerful study models, «what this technology would allow you to do is reprogram a skin cell, for example, from a Parkinson's patient... into a pluripotent cell and then in a petri dish redirect that cell into... a neuron» to treat that patient.
Modern geographers and cartographers are involved in diverse projects: tracking fleets of vehicles or products, helping customers locate a Dunkin' Donuts, modeling environmental scenarios such as oil spills, and studying the spread of disease.
The NIH Roadmap Project should help by allowing them to compare models of disease with reference samples.
Next, the research team will examine specifically whether these liver cells obtained from human embryonic stem cells in a dish help repair injured livers in preclinical animal models of liver disease.
«This research project is a prime example of how mouse models can help us to better understand cancer diseases in human beings,» says Sabine Harlander.
They generated a list of 18 genetic variations found only in people with Fuchs dystrophy, later narrowing the list to three most relevant to disease with the help of corneal laboratory models.
A volunteer models the noninvasive, electrical stimulation device used to help patients with Parkinson's disease.
Second, said Xia, he and his team now have created an effective model to help researchers understand colorectal disease and to develop and test therapies.
And we really need to understand the process if we want to create better disease models and to help the millions of patients waiting for more effective treatments.»
Using a pig model may help other scientists more effectively test treatments for colon cancer, type 2 diabetes and other chronic diseases.
Their findings could inform disease models and treatments, or even help design microscopic swimming robots.
«Using a pig model to study chronic diseases may help minimize drug failure rate.»
It could be used to diagnose almost any human disease, sometimes before symptoms appear, help identify new drugs, and even change the way we use animal models to understand disease.
With the help of various mouse models for pancreatic cancer, they have succeeded in elucidating the molecular pathways of tumor development in detail and have gained a better understanding of how various characteristics of the disease arise.
They also provide new information to determine when the mouse is an appropriate model to study human biology and disease, and may help to explain some of its limitations.
The authors developed a mathematical model accounting for disease progression, mortality, morbidity and the heterosexual transmission of HIV to help forecast future trends in the disease.
Probiotic treatment corrects memory problems in an Alzheimer's mouse model, suggesting that altering the microbiome may help delay the disease (Harpreet Kaur, abstract 126.23, see attached summary).
«iPSC model helps to better understand genetic lung / liver disease.»
Investigators led by Suma Prakash, MD, FRCPC, MSc (Case Western Reserve University) wondered whether a model called the «behavioral stage of change» model, which was originally used to help people quit smoking, might help patients with chronic kidney disease take action and make decisions about their dialysis options.
A zebrafish model of Dravet syndrome, a severe form of pediatric epilepsy, may help scientists quickly find drugs for the devastating disease.
To help develop a new solution, the multi-disciplinary research team included members with expertise in biomechanical engineering, pharmaceutical sciences, infectious disease modeling, polymer chemistry and health care innovation.
Maintaining the supply of a molecule that helps to nourish cartilage prevented osteoarthritis in animal models of the disease, according to a report published in Nature Communications online May 11.
I hope this approach will be a model to help us find new cures for other intractable disease.»
«Liver tissue model accurately replicates hepatocyte metabolism, response to toxins: Microfluidic device may help predict toxic effects of new drugs, study liver disease.»
The conclusions, obtained by tracking thousands of mobile phone users, could help researchers devise more accurate models of disease outbreaks.
«In collaboration with researchers from the University of Calgary and the University of British Columbia our team has developed a computer model to help doctors and their patients better understand how excess body weight contributes to reduced life expectancy and premature development of heart disease and diabetes,» says lead author Dr. Steven Grover, a Clinical Epidemiologist at the RI - MUHC and a Professor of Medicine at McGill University.
A new study shows that restoring the lipids that help keep lung tissue flexible and inflated can help slow disease progression in laboratory models of pulmonary fibrosis.
These quantifications might further help, and indeed convince, decision - makers across the world to decide on wide - scale introduction of prediction models and risk - based management for cardiovascular disease.»
«In the future, such detailed digital models of diseases and the structure of organs could be used to help diagnose conditions, understand the impact of surgical interventions and even run digital drug trials.
Additionally, the wheel lock and other animal model suggest that exercise during youth may help preserve muscle mass over the course of aging and lower the activity of genes associated with cardiovascular disease.
«Originally, we wanted to establish a disease model for FOP that might help us understand how specific gene mutations affect bone formation,» said first author Yohei Hayashi, PhD, a former postdoctoral scholar in Yamanaka's laboratory.
The third and final day of the 2016 Huntington's Disease Therapeutics Conference brings updates on cell replacement therapies including stem cells; and new ways to assess and model the progression of HD to help understand it and run crucial clinical trials.
For example, cross-model comparisons may help to pinpoint key cell types and molecules involved in lineage decisions, reveal evolutionary inventions, and may allow to interpret genetic disease models (for example in mouse) by mapping to human or other systems.
No doubt, knowledge of the mouse genome will help scientists design more effective mouse models for human disease and disorder.
Researchers have developed an array of mouse models to help scientists understand a whole collection of human diseases.
With the help of conditional and function - selective knockout mice for the glucocorticoid receptor (GR) the lab identified critical cell types and novel mechanisms for anti-inflammatory activities of glucocorticoids in different inflammatory disease models.
PHENOMIN - ICS services will ultimately help the scientific community in the use the mouse model, first to develop a complete functional annotation of the human genome and second to better understand human diseases and their underlying physiological and pathological basis.
«We hope this model will help us more readily uncover relevant factors that contribute to Huntington's disease and especially to find successful therapeutic approaches.»
«By generating in situ data with the help of citizen scientists, we envision the app serving supplementary data to scientists as they model mosquito population outbreaks,» says Rusty Low of the Institute for Global Environmental Strategies, «And equally important is the ability of the app to act as an enabling tool for citizen scientists who want to reduce disease risk in their communities.»
The new model should help scientists better understand the development of Huntington's — and provide better ways to identify and screen potential therapeutics for this devastating disease.
«Originally, we wanted to establish a disease model for FOP that might help us understand how specific gene mutations affect bone formation,» said first author Yohei Hayashi, PhD, a former postdoctoral scholar with Yamanaka's laboratory.
My research goal is to improve a mouse model of this disease by introducing pro-inflammatory cues, and to experiment with a method of decreasing inflammation in the eye to test the idea that localized control of inflammation could help protect vision.
To build upon the encouraging early discoveries, Helmsley renewed and expanded its Crohn's funding for the Institute in 2013 to begin new work with three major aims: 1) continue studies of individual genes to determine how genetic differences between Crohn's patients and healthy individuals contribute to the disease; 2) evaluate promising small molecules in disease - relevant studies and prioritize insights from genetics to help develop novel therapeutics; and 3) begin basic experimentation in animal models with Crohn's disease to provide the data necessary to begin testing new therapies in humans.
To help biological insights reach patients, Hieter co-founded, in 2014, the Canadian Rare Diseases: Models and Mechanisms National Network, a consortium that connects clinician scientists identifying gene mutations in patients that cause rare diseases to basic scientists analyzing the corresponding genes in model organisms.
Now he hopes to help fighting emerging bacterial disease, using new models for microbial gut infections.
The researchers hope that their modeling framework helps in the creation of more effective and lower cost public health responses to infectious disease.