Sentences with phrase «helps switch genes»

They noted that Tregs generally had high levels of a protein called Helios, a transcription factor that helps switch genes on and off.

It seems likely that they are there to help switch genes on or off, and to affect whether a gene is actively read or not.»

Not exact matches

Apparently broccoli contains potent nutrients which have the ability to switch «on» genes that prevent cancer development, and switch «off» other ones that help it spread.

Epigenetic tags help tell genes — stretches of DNA that act as biological instruction manuals — when to switch «on» and «off,» ultimately determining cell type and function.

Understanding these epigenetic changes provides a possibility to switch the genes back on, helping the body stop the aggressive tumors from forming.

These epigenetic switches and markers in turn help switch on or off the expression of particular genes.

«By switching certain genes on and off, prions could help bacteria survive environmental stresses rendering them less vulnerable to drugs, chemicals and other environmental assaults,» says investigator Ann Hochschild, professor of microbiology and immunobiology at HMS.

«Same switches program taste, smell in fruit flies: Findings help explain how complex nervous systems arise from few genes.»

Far from being junk, it's where molecular switches that help control gene activity are located.

The results suggest the human version of the FOXP2 gene may enable a quick switch to repetitive learning — an ability that could have helped infants 200,000 years ago better communicate with their parents.

In 2002 Joslin researcher Steven Shoelson knew that salicylates block the action of a protein called NFkB, a genetic master switch in the liver that helps launch a cascade of genes that cause the chronic, low - grade inflammation associated with diabetes.

The surprises are apparently far from over: Another kind of RNA can detect levels of small molecules that help a cell run smoothly, and switch genes on or off depending on the cell's needs.

The light - activated genetic switch could be used to turn genes on and off in gene therapies; to turn off gene expression in future cancer therapies; and to help track and understand gene function in specific locations in the human body.

A new study describes research helping tease out the mechanics of how the gut microbiome communicates with the cells of its host to switch genes on and off.

Writing online in the journal Molecular Cell, a team of researchers from the University of Wisconsin - Madison describes new research helping tease out the mechanics of how the gut microbiome communicates with the cells of its host to switch genes on and off.

Mutations in a gene that helps regulate when genes are switched on and off in cells have been found to cause rare cases of Wilms tumour, the most common kidney cancer occurring in children.

Many of these genes are usually switched off in adults, but previous research has shown that in many cancers — including prostate, ovarian, and brain cancer, melanoma, and leukemia — HOX genes are switched back on, helping the cancer cells to proliferate and survive.

The virus also switched off or lowered the expression of genes that code for a group of proteins called interferons, which help the body ultimately defeat the viral intruders.

A clearer picture of the events should help in designing drugs that switch off genes that cause disease and switch on those that fight it.

Though this genetic «dark matter» exists outside of our genes, scientists now appreciate that it helps control when and where our genes switch on and off.

Writing online Nov. 23 in the journal Molecular Cell, a team of researchers from the University of Wisconsin — Madison describes new research helping tease out the mechanics of how the gut microbiome communicates with the cells of its host to switch genes on and off.

Myriad control switches help to arbitrate how genes get expressed in different cells and tissues, and those switches are often triggered by maternal diet, toxic exposures and many other environmental factors.

Specifically, they analyzed the tumors» epigenome, an array of molecules that covers the surface of DNA and helps regulate gene activity, acting like a control switch to decide which genes are active or inactive in the cell.

During memory formation, certain genes must be switched on and off at very specific times in order to generate proteins that help neurons lay down new memories.

With the help of this grant, we are generating mice engineered to switch off the APOE gene only in microglia and performing molecular profiling without having to isolate microglial cells first.

Other repeated sequences, more than one hundred letters long, appear to help genes move around, allowing «silent genes» to be moved next to an «on» switch where they become active.

However, in the absence of VHL, HIF - 1 is active even when oxygen is plentiful and switches on genes that help a cell take up more glucose.

Tinkering with gene switches can have a profound effect on how they behave, and labs around the world are now scanning the genome in hopes of identifying epigenetic modifications — sometimes called «marks» or «tags» — that could serve as biomarkers, helping to predict and identify a wide range of conditions.

TBX5 produces a protein of the same name that acts as a critical switch, helping to turn other genes involved in heart development on or off.

Curcumin switches on liver genes that keep glucose levels in check, improves the pancreas's ability to make insulin and helps to slow down the metabolism of carbohydrates after meals.