This gave a mixed population of cells with 20 % expressing CD34,
a hematopoietic stem cell marker, with some co-expression of endothelial cell markers (CD31, Flk1, and VE - cadherin).
Not exact matches
When Busch turned on the
marker in adult animals, it became visible that at least one third (approximately 5000
cells) of a mouse's
hematopoietic stem cells produce differentiated progenitor
cells.
Nearly 30 years after the discovery of the
hematopoietic stem cell, Stanford researchers have found a
marker that allows them to study the version of these
stem cells that continues to replicate.
Hematopoietic stem cells express the
markers CD34 and CD133 and can repopulate a myeloablated recipient after allogeneic or autologous transplantation.
Finally, within the fractionated
cell populations, there was evidence for coexpression of lineage specific
markers alongside of pluripotency genes, similar to lineage priming described first in
hematopoietic stem cells [15].