Sentences with phrase «hemophilia into»

For instance, from the manufacturer's point of view, an «improvement in the safety of health care» and a «better integration of patients with hemophilia into a normal social life» already arise through market entry.

Not exact matches

A Shire buy would give it a way into the hemophilia market, as well as more drugs for combatting cancer and other illnesses.

Moreover, the results may transcend the bloating and discomfort of lactose intolerance: The technique could serve as a way to transform the gut lining into a factory for replacing missing proteins in other genetic disorders such as hemophilia, says pulmonologist Eric Alton of the Imperial College School of Medicine in London.

These multigene interactions are subtler and knottier than the single gene drivers of diseases such as hemophilia and cystic fibrosis; spotting them calls for statistical inspiration and rigorous experiments repeated again and again to guard against introducing unproven gene tests into the clinic.

Her hemophilia patients, like most of us, carried antibodies to AAV, and their immune systems flew into high gear when they received the engineered virus.

To verify that the process worked, the endothelial cells with the inversion - corrected genes were transplanted into F8 deficient mice (mice with hemophilia A) and the mice started producing the F8 clotting factor on their own, which essentially cured them of hemophilia A.

Concerns about immunological consequences of rAAV - mediated gene transfer were substantiated by the outcome of a clinical trial in which human hemophilia B patients were infused into the liver with rAAV -2-F.

We entered into an agreement with Bayer to research, develop and commercialize AAV gene therapy products for treatment of hemophilia A.