Sentences with phrase «hepatocyte differentiation»
The GMP - ready hepatocyte differentiation protocol is published in Stem Cell Reports.
https://www.biolamina.com/
Here, Kate presents her work on that show that culture of human ES cells on human recombinant laminin - 521 and laminin - 111 substrates significantly improve hepatocyte differentiation, maturation, function and stabilization of phenotype compared to Matrigel cultured cells.
ES derived hepatocyte differentiation on laminins represent significant improvement of metabolic activity and functional organisation
To address this problem, we developed a robust hepatocyte differentiation protocol — which promotes a highly synchronized differentiation pattern across multiple hiPS cell lines [1]-- and a novel maintenance medium, which enables the long - term culture of our hiPS cell - derived hepatocytes.
Not exact matches
Human iPS cell - derived hepatocytes differentiated with our robust differentiation protocol and cultured using our novel maintenance medium provide an inexhaustible, consistent supply of functional hepatocytes that can be used to advance the understanding of diseases related to dysfunction in liver metabolism, including NAFLD / NASH, type 2 diabetes, and metabolic syndrome.
Human iPS cell - derived hepatocytes differentiated with our robust differentiation protocol and cultured using a novel maintenance medium provide an inexhaustible, consistent supply of functional hepatocytes that can be used to advance the understanding of diseases related to dysfunction in liver metabolism, including NAFLD / NASH, type 2 diabetes, and metabolic syndrome.
One Standardized Differentiation Procedure Robustly Generates Homogenous Hepatocyte Cultures Displaying Metabolic Diversity from a Large Panel of Human Pluripotent Stem Cells.