Sentences with phrase «hepatocyte gene»

Not exact matches

The researchers then tested the particles» ability to shut off the gene for a blood clotting protein called Factor VII, which is produced in the liver by cells called hepatocytes.

From one end of the sinusoid to another, the hepatocytes have different metabolic functions, often controlled by external factors and gene expression.

Overexpression of variant PNPLA3 gene at I148M position causes malignant transformation of hepatocytes via IL -6-JAK2 / STAT3 pathway in low dose free fatty acid exposure: a laboratory investigation in vitro and in vivo.

However, hiPS cell - derived hepatocytes are only useful as an in vitro model system and for gene editing applications if they recapitulate critical hepatocyte functions.

Hepatocyte nuclear factor 4α (HNF4α) is a transcription factor required for liver development and the control of expression of liver - specific genes, and it is associated with several critical metabolic pathways [3].

The researchers found that patients from MODY3 families had one of several different mutations in the gene for hepatocyte nuclear factor 1 alpha (HNF -1-alpha) but healthy subjects had normal copies of the gene.

Hepatocyte growth factor (HGF) gene therapy could be used to treat patients with severe peripheral arterial disease (PAD), suggest results...

«Amino acid availability to the hepatocytes is essential for IGF - I gene expression».