Sentences with phrase «hepatocytes compared»
Ag - NPs coated with galactose and mannose were considerably less toxic to neuronal - like cells and hepatocytes compared to particles functionalized by glucose, ethylene glycol or citrate.
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They based their approach on a system they had previously developed for studying the hepatitis C virus, in which they were able to successfully infect human hepatocytes with the virus and use it to compare antiviral regimens.
Here, Kate presents her work on that show that culture of human ES cells on human recombinant laminin - 521 and laminin - 111 substrates significantly improve hepatocyte differentiation, maturation, function and stabilization of phenotype compared to Matrigel cultured cells.
The Liver - Chip showed improved viability and hepatic function compared to conventional hepatocyte culture systems over long - term culture.
To highlight the potentially important role of 3D culture conditions, the authors compared 2D monolayers of hepatocyte progenitors, fetal liver stromal cells, or adult bone marrow - derived stromal progenitor cells to their 3D counterparts cultured on liver extracellular matrix (3D - ECM) constructs.
Overall binding of both [3H] TRL preparations was significantly reduced in hepatocytes isolated from Ldlr — / — Lrp1fl / fl Alb - Cre + mice compared with hepatocytes isolated from Ndst1fl / fl Alb - Cre + mice (Figure 10).
Binding and uptake of radiolabeled ApoC - III — depleted TRLs was significantly increased in hepatocytes isolated from Ndst1fl / fl Alb - Cre + mice (i.e., in mice expressing both LDLR and LRP1) when compared with ApoC - III — bearing TRLs (Figure 10).
Galactose and mannose - coated nanoparticles were considerably less toxic to both neuronal - like cells Neuro - 2A and hepatocytes, compared to particles functionalized with glucose, ethylene glycol or citrate.