Sentences with word «heritable»

An experimental assisted reproduction technique that could allow some families to avoid having children with certain types of heritable disease should be allowed to go forward in the United States, provided it proceeds slowly and cautiously.

One highly heritable disease, Fuchs endothelial corneal dystrophy, causes painful corneal swelling and blurred vision.

Evolution — the change in heritable traits over successive generations — has long served as one of the central tenets of biology.

OBJECTIVE Bipolar disorder is a highly heritable condition.

They should be screened for heritable conditions such as hip and shoulder dysplasia, demodecosis (predilection for mange), hernias, and cryptorchidism (un-descended testes).

Epigenetics is the study of heritable changes in gene function that do not involve changes in the DNA sequence.

In light of this shortcoming, some investigators see room for an increased focus on an alternative explanation for heritable traits: epigenetics, the molecular processes that control a gene's potential to act.

«I have been concerned for some time about the increasing incidence of heritable disorders in many pure breeds of dog,» says Pederson.

When purchasing a purebred, find a responsible breeder to ensure that the dog is sound and certified free of certain heritable genetic diseases.

The Canine Eye Registration Foundation is an organization that was founded by a group of concerned, purebred owner / breeders who recognized that the quality of their dog's lives were being affected by heritable eye disease.

von Borczyskowski et al., confirmed that Swedish adoptees carry a higher burden of heritable risk for suicidality, that is, biological parents» substance abuse, suicidal behavior, and psychiatric illness explained one - third of increased risk of suicide attempt in domestic adoptees.

Here are some of Thornton's signs of a good breeder: completely answers questions about the breed, raises puppies in the home and not in a pen or in filthy conditions, and has a sales contract that includes a minimum one - year health guarantee against life - threatening or crippling conditions caused by heritable defects.

I explain to my students that evolution is a process that follows many rules, foremost among them that certain random changes in heritable factors provide their possessors with advantages in coping with an ever - changing environment.

Participate and / or cooperate in research studies into heritable defects affecting the English Springer Spaniel.

I wanted to make something that resonated more with heritable information — «autobiographical information» might be a better way of saying it.

He studies rare disease mutations and common heritable traits and disorders, such as fear - learning and autism, using mouse models as well as genomic and bioinformatic approaches.

Fragile X syndrome, the most common heritable cause of intellectual disability and a frequent cause of autism, is characterized by abnormalities of the FMR1 gene that are difficult to analyze.

Having family members with these pre-menopausal cancers increase your chances of genetically heritable mutations that increase your risk of developing these cancers.

It is the parent clubs of pure breeds that fund studies and provide DNA for research on degenerative myelopathy, von Willebrand's disease, dilated cardiomyopathy, hip dysplasia, and other heritable disorders.

While PrediXcan can discover links between genes and traits in a high - throughput manner, Im notes that because it creates estimates based on genome sequence data, it is most accurate for strongly heritable traits.

It provides a variety of reports to help educate owner / breeder on heritable eye disease questions, healthy breeding stock, and breed - specific eye problems.

The age of seven was chosen as the cutoff for the last passing CERF certificate since that was originally recommended by Dr. Kirk Gelatt as the age to differentiate between heritable cataracts and those which would be considered to be attributed to normal age related changes.

Cross-fostering experiments have proved that these maternal effects are not heritable in the narrow sense, but are consequences of the characteristics of maternal care received in the first week of life.

The study uncovered «tremendous variation in recombination rates over all genomic scales considered and in particular heritable variation in hotspot use,» the authors conclude.

Demographers and epidemiologists have estimated that the length of human lifespan is a moderately heritable trait, with the offspring of individuals achieving old age being more likely to also achieve old... >> MORE

The risk of developing autism, according to one study, is more than 90 percent heritable because the concordance for autism is high in monozygotic twins and low in dizygotic twins.

Bipolar disorder (BD) is one of the most heritable psychiatric conditions and is associated with high suicide risk.

Empirical evidence suggests that attachment security in mother — infant bonds builds on heritable differences in sensitivity to isolation [14].

Testicular germ cell tumor (TGCT) is a highly heritable cancer primarily affecting young white men.

«Mutations in the protein progranulin are found in many cases of heritable forms of frontotemporal dementia,» said Li Gan, PhD, associate director of the Gladstone Institute of Neurological Disease and senior author on the study.

Other health problems include heritable lack of enamel (enamel hypoplasia) and other dental issues, progressive retinal atrophy, glaucoma, legges perthes disease, luxating patellas, and hypothyroidism.

The surveys include questions regarding heritable aspects like eye color, widow's peak hairlines and even whether an individual has the ability to roll his or her tongue.

Before they had to deal with heritable breast cancer and its lead agent, the BRCA1.185 delAG mutation, a previous generation of Ashkenazim had confronted Tay - Sachs, another genetic disease.

«We're talking about an incredible synergy between technology and biology, about very simple improvements — pasteurization, a general reduction of pollutants, cleaning up our water supply — producing heritable effects across populations faster than ever before.

In summary, the CERF clinic was successful and helpful in identifying some potentially heritable problems in a small portion of the dogs presented for examination.

Dr. Gibbs also gave an overview of their investigations into heritable variants in pediatric cancers (in collaboration with MD Anderson).

The same study also shows that mink behaviour is a more heritable trait than hitherto believed.

Examination of copy number variants, alternative splicing, epigenetics and genetic variants are needed to characterise the interactions between heritable and non-heritable mutations for an insight into the full genomic complexity of these little - understood disorders.

Protein evolution expert Dan S. Tawfik of Weizmann Institute of Science, in Rehovot, Israel, calls heritable recombination «a powerful approach that can open exciting opportunities.