To improve the pharmaceutical properties of bicyclams, one or both rings were replaced by smaller
heterocyclic groups.
Not exact matches
Ferreira's previous research found that beer marinades effectively reduce levels of another
group of carcinogens called
heterocyclic amines (HCAs), which form when amino acids, sugars, and creatine in meats react at high temperatures.
In order to avoid a second protonation at the physiological pH, a series of aminomethyl - substituted analogues, in which the second amino
group was part of a
heterocyclic ring or an aromatic system, were synthesized.
CXCR4 antagonists in which a substituted benzylic aminomethyl
group or a
heterocyclic aminomethyl moiety replacing the butyl amine residue showed potent antiviral activity [88].
The Term Chelate: The term chelate was first applied in 1920 by Sir Gilbert T. Morgan and H. D. K. Drew, who stated: «The adjective chelate, derived from the great claw or chele (Greek) of the lobster or other crustaceans, is suggested for the caliperlike
groups which function as two associating units and fasten to the central atom so as to produce
heterocyclic rings.»