Sentences with phrase «heterotrimeric guanine»

Heterotrimeric guanine nucleotide — binding protein (G protein)-- coupled receptors constitute the largest family of eukaryotic signal transduction proteins that communicate across the membrane.

Hormones and neurotransmitters may mediate common responses through receptors that couple to the same class of heterotrimeric guanine nucleotide — binding (G) protein.

β - Arrestins, originally discovered in the context of heterotrimeric guanine nucleotide binding protein — coupled receptor (GPCR) desensitization, also function in internalization and signaling of these receptors.

The β2 - adrenergic receptor (β2AR) is a well - studied prototype for heterotrimeric guanine nucleotide — binding protein (G protein)-- coupled receptors (GPCRs) that respond to diffusible hormones and neurotransmitters.

Heterotrimeric guanine nucleotide - binding regulatory proteins (G proteins) dissociate into guanosine triphosphate (GTP)- bound alpha subunits and a complex of beta and gamma subunits after interaction with receptors.