Sentences with phrase «high affinity cells»

Not exact matches

Given that the newly discovered protein FGB1 has such a high affinity and specificity to beta -1,6-glucans from fungi cell walls, it is possibly suitable for the diagnosis of human infections.

This group's achievement reverses the conventional wisdom that memory B cells are induced by high - affinity cells, possibly greatly influencing vaccine strategies targeting memory B cells.

Kong and Crotty's team discovered that ICOS recruits the signaling TBK1 enzyme, which activates certain genes in Tfh cells, thus beginning the whole process of high - affinity antibody production.

«Tfh cells control the whole process of generating high affinity antibodies, and ICOS is a receptor molecule strongly required for Tfh cells to work.

In germinal centers — the sites within lymph nodes where mature B cells cluster — B cells proliferate and undergo hypermutation of their antibody genes to generate high - affinity antibodies.

In the current study, the researchers used high - affinity antibodies to «label» the cannabinoid receptors so they could be seen using various microscopy techniques, including electron microscopy, which allowed very detailed visualization at individual synapses, or gaps between nerve cells.

There are also differences in the affinity of different transporters for specific drugs: for example, the high - affinity transporters OCT1 and / or OCTN2 are functional at the basolateral membrane of rat Sertoli cells, whereas the low - affinity transporters OCT3 and / or OCTN1 are functional at the apical membrane (43).

This is accomplished by combining high - throughput generation of affinity - purified antibodies with protein profiling in a multitude of tissues and cells assembled in tissue microarrays.

They claimed that witch hazel had a high affinity for human cells and cell membranes and hence was highly equipped to defend them against reactive oxygen species (free radicals).

Witch hazel antioxidants even have a particularly high affinity for human skin cells.

Being lipophilic (having an affinity for lipids), they leave the bloodstream quickly, passing through biological membranes and concentrating in cells, including brain cells.7 Mercury is especially drawn to high - sulfur organelles (specialized cell structures) such as mitochondria.

Mercury has a high affinity for many thiol enzyme bonds in your body and it causes inflammation and cell death when it binds to them.

So to generate autoimmunity against Neu5gc incorporated in human cells, B cells must first be triggered to form high - affinity anti-Neu5gc antibodies by meeting bacterial pathogens who have incorporated Neu5gc into their cell walls.