The studies (though conducted almost entirely in men) showed that there's a definite interaction between flibanserin and alcohol, with an increased number of side effects such as dizziness and fainting at moderate and
high alcohol doses.
One study found an increased sleep time at a low alcohol dose (i.e., 0.16 g / kg) but detected no such effect at
higher alcohol doses (i.e., 0.32 and 0.64 g / kg)(Stone 1980).
Not exact matches
There are some toxins, such as
alcohol, that your body can deal with at a low level and that will kill you only at
high doses.
Alcohol acts as a narcotic — first, in suppressing the
higher mental functions and then, as larger
doses are taken, in reducing a person to the animal level and finally to unconscious vegetative immobility.
Experiments on rodents suggested that repeated
high doses of
alcohol destroy neurons in the hippocampus.
Participants engaged in three sessions, in which they were given a placebo drink with only the smell of
alcohol, a low
dose of
alcohol or a
high dose.
When the researchers
dosed the rats with
higher levels of
alcohol through injections in an effort to mimic the effects of binge drinking, however, the results were very different.
These long - term effects of
alcohol all stem from the fact that in
high doses, it's actually toxic.
But, as Peter of Hyperlipid cautions, diets
high in sucrose or
alcohol can increase the load on your liver when paired with
high dose fish oil supplementation.
Second,
alcohol consumed in
higher doses can reduce the ability of white cells to kill germs by suppressing their ability to multiply.
However,
high doses of acetaminophen can lead to liver problems, especially if taken with
alcohol.
But in
higher doses over time,
alcohol decreases fat burning and the excess calories from
alcohol are stored as belly fat.
Elevated cortisol (or cortisone, see below) is associated with Cushing disease, unipolar depression, sleep deprivation, anxiety, panic disorder, PTSD in its early stages, exogenous cortisol supplementation,
high -
dose licorice root supplementation, intense physical exercise, and acute ingestion of
alcohol.
Compounds that bind to GABA receptors (
alcohol, benzodiazepines) can significantly reduce anxiety, produce moderate levels of euphoria and induce sleep in
higher doses.
yield breath
alcohol concentrations (BrACs) as
high as 0.105 percent.3 (3Breath
alcohol concentrations are another way of quantifying
alcohol levels in the body and are approximately the same as blood
alcohol concentrations after a given
alcohol dose.)