82, 83) and
high breast density, whether assessed by a volumetric method or by mammography, is similarly positively associated with breast cancer risk (2, 84).
One cause of false - negative results is
high breast density.
The study included 266 healthy postmenopausal women with
high breast density detected by routine mammograms.
The study included 266 healthy postmenopausal women with
high breast density detected by routine mammograms.
Professor Michael Lisanti, from The University of Manchester — part of Manchester Cancer Research Centre, said: «We know
that high breast density can greatly increase a woman's breast cancer risk as well as other factors such as aging, family history and presence of mutations in genes such as BRCA 1 and BRCA 2.
Women with
higher breast density — detected on mammograms — have more compacted breast tissue and are more likely to develop breast cancer, but until now the reasons for this have been unclear.Manchester scientists, funded by leading UK research organisation Breakthrough Breast Cancer, worked with IBM researchers and academics in the USA and Cyprus to uncover the biological mechanisms at play.
Of the 230 detected breast cancers, almost half were from the group with the lowest ranked breast density, while slightly less than 3 percent came from women in
the highest breast density category.
Conclusions: In our study, adolescent intakes of higher saturated fat and lower mono - and polyunsaturated fat are associated with
higher breast density measured approximately 15 years later.
Not exact matches
«The finding that MBI substantially increases detection rates of invasive cancers in dense
breasts without an unacceptably
high increase in false positive findings has important implications for
breast cancer screening decisions, particularly as 20 states now require mammography facilities to notify women about
breast density and encourage discussion of supplemental screening options,» says Dr. Rhodes.
The study team explained that blocking the JNK1 network could feasibly reduce the risk of, and potentially prevent,
breast cancer in women with
high density breast tissue.
Increased
breast density is associated with a
higher risk of
breast cancer.
There is a strong connection between
breast cancer and the
high rate of
breast density.
This signature showed that a cellular communication network called JNK1 was activated to a greater extent in fibroblasts from
high density breast tissue.
A strong link was found between low
breast density and
high expressions of HA and its synthesizing enzymes.
Because cancer also appears as white on a mammogram, a
high degree of
breast density can make it difficult to spot tumors and other abnormalities.
Furthermore, walking for exercise reduces risk of hip fracture in the elderly, reduces risk of cataracts, increases bone
density, reduces risk of falling, improves balance, improves flexibility, improves back and lower extremity strength, reduces low -
density lipoprotein (LDL) cholesterol (this is the bad type of cholesterol), increases
high -
density lipoprotein (HDL) cholesterol (this is the good type of choleserol), reduces risk of heart disease, reduces risk of stroke, and reduces risk of colon and
breast cancers.
Olive oil's health benefits include: decreases * risk of
breast cancer and its recurrence, lowers the level of LDL (low
density cholesterol, «bad cholesterol») and increases * the level of HDL (
high density cholesterol, «good cholesterol»), reduces * chances of developing heart - related disease.
Research shows healthy women at
high risk of
breast cancer who took the medication for four - and - a-half years lowered their
breast density by 6.4 percent, Diorio relates.
A recent study (2) showed that the current use of multivitamins and minerals in premenopausal women was associated with a significant 5.3 %
higher mean mammographic
breast density (after adjustment for potential confounders), which is strongly and positively related to
breast cancer risk.
Assessing the usefulness of a novel MRI - based
breast density estimation algorithm in a cohort of women at
high genetic risk of
breast cancer: the UK MARIBS study