Sentences with phrase «high content screening»

Similarly, disease - specific fluorescence markers are finding their way back into basic research in high content screening applications.

An automated cell fixation and staining platform (Thermo, Biotek) is used for High Content Screening campaigns (HCS)

In order to use these DM1 - specific biomarkers to develop new therapeutic treatments, we successfully developed technical assessments of miniaturization to realize high content screenings based on detection of the nuclear aggregation of the mutant mRNA.

The consequences of gene extinction on DM1 phenotype is then monitored at the molecular level by quantitative PCR or at the cellular level by high content screening in 96 or 384 - well plate format.

DA - HCS enables the reduction of expensive antibodies and reduces the volume of precious cells needed in high content screening assays.

Previously, she developed an innovative High Content Screening HTS platform, OncoPanel, to profile therapeutic cancer agents across 240 human tumor cell lines at Ricerca Biosciences (formerly MDS Pharma Services).

246/3: 00 Quantitative cell image - based high content screening identifies brain permeable small molecules that rescue peroxisome assembly defects in cells from patients with Zellweger spectrum disorder.

DropArray offers three platforms that address unmet needs for cell processing with flow cytometry (DA - Cell), miniaturizes and improves magnetic bead - based assays (DA - Bead), and enables reduction of cells and expensive reagents for high content screening (DA - HCS).

His research interests include the assembly of proteins into the endoplasmic reticulum membrane, the molecular mechanisms by which Bcl - 2 family proteins regulate apoptosis, high content screening, the development of new fluorescence microscopes, and automated image analysis.

The measurement tools for high content screening were installed, especially an automated imager and quantitative PCR on 384 - well plates.

What can high content screening, combined with micropatterning, tell researchers about the efficacy of a cosmetic active?