Patients who receive HSCT receive
high doses of chemotherapy, with or without radiation, followed by infusion of hematopoietic stem cells (HSCs)-- rare cells that reside within the bone marrow and are capable of producing all varieties of blood cells.
Traditional treatment of pediatric APL has included
high doses of anthracycline, increasing patient's risk for cardiac toxicity.
An 18 - month trial of
high doses of the same three vitamins used here showed a slowing of cognitive decline in patients with mild Alzheimer's disease, although not in patients with moderate Alzheimer's disease [45].
For its new study, Suvorov's team exposed pregnant mice to
high doses of one of three common chemicals.
The addition of
high doses of a form of vitamin A could help make chemotherapy more successful in treating pancreatic cancer, according to an early study by Queen Mary University of London.
«It's been known for some time that regular
high doses of THC during adolescence, a period when our brains are still developing, is potentially harmful for memory function.
To hunt for possible molecular markers, researchers started with an African strain of P. falciparum parasites that had been repeatedly exposed to artemisinin until it was able to survive
high doses of the drug in the lab.
Also, extremely
high doses of DHEA have actually led to lengthening of the circadian period.
This treatment is a way of giving
high doses of chemotherapy and replacing blood - forming cells destroyed by the cancer treatment.
For this study, Sisodia and his team administered
high doses of broad - spectrum antibiotics to mice over five to six months.
Because
high doses of opioids have the potential to cause respiratory arrest or other dangerous side effects, doctors may hesitate to give patients as much of the drugs as they need to relieve their pain, says David Soergel, chief medical officer at Trevena.
Douglas J. Schwartzentruber and colleagues at The University of Texas MD Anderson Cancer Center demonstrate that patients with metastatic melanoma receiving
high doses of interleukin - 2 (IL - 2) plus a gp100 peptide vaccine had significant improvement in overall clinical response, providing further validation for vaccine approaches to cancer treatment.
Some archaea are nearly unsensitive to
high doses of gamma rays and have the ability to fully regenerate their genome.1 Consequently the experiments showed no significant change of results.
Mice that are unable to fully activate the powerful tumor suppressor p53 are resistant to
high doses of radiation.
As a result, these animals became very resistant to the deleterious effects of
high doses of radiation.
Keep in mind that extremely energetic stars (those of types O through A) will blast their planets with
high doses of ultraviolet radiation, which is detrimental to the evolution of life.
In fact this is one of the explanations for why a pregnant woman goes into premature labor and they can't reverse it — they will empirically treat with
high doses of steroids because they know the lung outcome of the infant is better.
In patients with kidney disease,
high doses of iron may be needed to bind phosphates into the bloodstream.
When the researchers gave
high doses of cortisone to these mice, the mice built typically strong and healthy bones.
A large number of lab studies using rats and mice exposed to
high doses of BPA failed to show measurable effects on key aspects of reproductive development, function and behaviour.
«By exposing the patients to chemicals chosen to only incorporate the smelly component, we were able to stimulate them with really
high doses of the smell without them waking up.»
SBRT permits the precise and accurate delivery of
high doses of radiation over a shorter period of time (typically 1 to 2 weeks) than with conventional radiation treatments.
They discovered that although
high doses of thalidomide stop angiogenesis, lower doses actually fortify the blood vessels by spurring cell growth.
Among those with cancer, having diabetes or receiving
high doses of doxorubicin — a type of chemotherapy — were found to be especially risky for future heart health.
Neel hopes
high doses of vitamin C will become part of cancer therapies, although this would involve injections rather than diet or supplements.
When insects from such a species carry two copies of a resistance gene, they can survive
high doses of Bt.
People with severe asthma, in which the airways become inflamed and constrict to impair breathing, do not get better even with
high doses of corticosteroids, the mainstay of treatment for typical asthma, explained Anuradha Ray, Ph.D., professor of medicine, Pitt School of Medicine.
To investigate this life - saving stitchwork, Abraham Minsky and colleagues at the Weizmann Institute of Science in Rehovot, Israel, and elsewhere exposed thousands of bugs to
high doses of radiation.
I read with interest the report that taking very
high doses of vitamin C slows the progression of leukaemia in...
Water bears, or tardigrades, have been recorded surviving the vacuum of space,
high doses of radiation and pressure.
Female rats exposed in the womb to
high doses of several chemicals — including pesticides and plasticizers — developed cysts resembling human polycystic ovarian syndrome and premature menopause, according to the study published in PLoS One in July.
Patients with severe asthma often require
high doses of steroid - based treatments that can significantly impair their quality of life.
Of course, farmers have typically planted, say, GM corn, because it can tolerate
high doses of weed - killer.
The landmark Age - Related Eye Disease Study (AREDS) found in 2001 that a specific formula of nutritional supplements containing
high doses of antioxidants and zinc could slow the worsening of AMD in those who have intermediate AMD and those with advanced AMD in only one eye.
They selected the concoction now called ZMapp and gave it to three groups of six monkeys; all received intramuscular injections of
high doses of Ebola virus.
Looking forward, the researchers are now hoping to examine other Ediacaran sediments from around the globe to verify the rapid reversals» signal, along with hunting for biological or chemical evidence for
high doses of UV radiation in the fossil record.
Sceptics point out that in Hungary, where parts of the population are exposed to
high doses of arsenic in the water, there is as yet no evidence of increased cancers.
A small animal study suggests that
high doses of the virus, called adeno - associated virus 9, can cause severe liver and neuron damage in young monkeys and pigs.
Wartman stabilized his GVHD with
high doses of prednisone and the IL - 2 — dampening drug tacrolimus, but that wasn't enough suppression to resolve his symptoms.
«Here, we verified convincingly that increased redox active metal ions in cancer cells were responsible for this differential sensitivity of cancer versus normal cells to very
high doses of vitamin C.»
Over the course of seven hours, animal radiologist Anthony Fischetti subjected them to
high doses of radiation in the hospital's CT scanner.
Pou was a New Orleans doctor who was arrested but ultimately not indicted for second - degree murder after she gave lethally
high doses of painkillers to critically ill patients in the days following Hurricane Katrina.
The image quality provided by the latest digital detectors permits radiologists to see fine detail without resorting to
high doses of radiation.
The difference was particularly pronounced for people on
high doses of immune - suppressant drugs.
Taking
high doses of vitamin D2 caused something to happen at the muscle level that isn't in the best interest of the athletes.
The Nobel prizewinning chemist Linus Pauling enthusiastically promoted
high doses of vitamins without waiting for the evidence, the public lapped it up and a whole new industry sprang up to meet demand.
Proton beam therapy has the ability to deliver
high doses of radiation directly to a tumour site with very little radiation being absorbed into healthy tissue.
Two days after infecting groups of guinea pigs with a lethal dose of Lassa virus, the scientists treated the rodents daily for two weeks with either ribavirin, low doses of favipiravir, or
high doses of favipiravir.
Lloyd - Jones's editorial is based on a large new study published in the journal that looked at adults, ages 50 to 80, with cardiovascular disease who took extended - release niacin (vitamin B3) and laropiprant (a drug that reduces face flushing caused by
high doses of niacin) to see if it reduced heart attack and stroke compared to a placebo over four years.
Previous research looked at
high doses of purified resveratrol to study its potential to prevent cancer.