Sentences with phrase «high false discovery»

It is clear, however, that evidence of an excess of amino acid substitutions (at least from site - by - site tests) is no longer a sufficiently convincing demonstration of selection, not only because a high ratio could result from selection on synonymous mutations rather than positive selection on proteins [5], but also because there is potentially a high false discovery rate of selected sites [6].

Not exact matches

Using 5 % false discovery rate in ANOVA calculation in any of the 3 comparisons (CGR8 vs. E14TG2a vs. R1), there are 137 genes (0.9 % of the analyzed transcripts) that show a 2-fold difference or higher in expression levels among the three lines; 34 of these genes are > 2-fold higher or lower expressed in E14TG2a, 5 in CGR8 and 11 in R1 cells.

A 5 % false discovery rate in ANOVA calculation and a 2-fold difference or higher in any of the 3 comparisons (CGR8 vs. E14TG2a vs. R1) led to a set of 137 differentially expressed genes (0.9 % of the analyzed transcripts).