Previous studies had
linked high genetic diversity within bacterial infections or in cancers with poor outcomes for patients treated with antimicrobial or chemotherapy drugs.
The scientists, part of a team headed by researchers at Laval University in Quebec, used climate reconstructions from 21,000 years ago to the present to predict where caribou habitat would likely exist and they matched reservoirs
of high genetic diversity to areas with the most stable habitat over time.
Higher genetic diversity in African populations, combined with underrepresentation of non-European populations in control datasets, result in an excess of rare and apparently rare variation in these individuals, rendering variant interpretation more challenging.
Ancient gray whale sequences
show high genetic diversity, but this diversity is not randomly distributed with respect to today's haplotype distribution (Figure 3).
For a cancer with
very high genetic diversity (like AML) however, the unintended effect of treatment is often to select for the most aggressive, resistant cells, clearing away their competitors and furnishing them with all the resources they need to flourish.
As evidence, the scientists from Dresden highlight the
much higher genetic diversity — compared to their more southerly relatives — of the Grass Snakes in Northern Germany and Scandinavia.
The finding, published Nov. 9, 2015, in the Proceedings of the National Academy of Sciences, suggests that even microscopic tumors are likely to contain
extremely high genetic diversity.
«
High genetic diversity in the more connected areas of Panama indicates that transport networks may facilitate the mixing of different molecular lineages,» said Kelly Bennett, post-doctoral fellow at STRI.
Kamdem said
the high genetic diversity among mosquito species and their ability to swap genes makes it difficult to stop the development of insecticide - resistant groups.
Scientists at the Wellcome Trust Sanger Institute and the Institute for Research on Cancer and Ageing of Nice in France, show that
high genetic diversity can prime new mutations that cause drug resistance.
Researchers reported that the domestic ferrets in North America and Australia had extremely low genetic diversity, whereas ferrets in Europe had
higher genetic diversity, as periodic hybridization with wild polecats appears to occur.
The authors speculate that reasons for the lower losses compared to those of other countries may be due to
a high genetic diversity in their honey bees, regular replacement of queen bees by the beekeepers, and because the average size of beekeeping operation is small, meaning that beekeepers can pay close attention to their hives, in particular to the way they control the parasitic varroa mite.
T. gondii has
high genetic diversity, with hundreds of genotypes existing globally.
«On a related note, though, researchers have tied higher population density in Africa as also another explanation for
the higher genetic diversity on the continent.»
Rene Vellanoweth, an archaeologist, believes that inbreeding depression can be managed by mixing the different island fox subspecies populations much as the indigenous peoples did, by moving them from island to island, creating
a higher genetic diversity and assisting them in recovery.
«(i) Managing for novel ecosystems... (ii) Retaining ecological memory... (iii) Conserving regions of
high genetic diversity... (iv) Developing resilience to threshold events...»
Scientists working at the Smithsonian Tropical Research Institute (STRI) think one group of survivors, corals in the genus Orbicella, will continue to adapt to future climate changes because of
their high genetic diversity.