Sentences with phrase «high heritability of»

In addition, given the high heritability of antisocial behaviour problems in the presence of high levels of CU traits, it was hypothesized that CU traits would be significantly associated with functional polymorphisms of the serotonin - system.

Furthermore, the high heritability of CU traits and their association with more chronic and serious aggression and antisocial behaviour problems make them a strong candidate for the driving force behind the familial transmission of aggressive behaviour that Halperin et al. [38] argue is mediated, in part, by reduced central serotonin function.

Moreover, given the high heritability of both conditions (Faraone et al. 2005; Freitag 2006), it is of note that family and twin studies show co-heritability (Lichtenstein et al. 2010; Lundström et al. 2011; Mulligan et al. 2009a; Nijmeijer et al. 2009; Taylor et al. 2012).

The best - fitting model revealed a high heritability of ADHD [0.88, 95 % confidence interval (CI) 0.83 — 0.92] for the entire sample.

Although glaucoma itself was not shown to be inherited, the close association between the predisposing condition (goniodysgenesis) and the disease and the high heritability of goniodysgenesis can be taken to indicate that glaucoma is inherited.

In our study, an 18.3 % incidence of idiopathic epilepsy was found among related Irish wolfhounds with a high heritability of 0.87 for the trait.

Since we have estimated a moderate to high heritability of the condition it will be possible to use selective breeding to reduce the incidence of disease.

Not exact matches

Despite high heritability estimates of 45 % in childhood and 80 % in adulthood, only a handful of genes had previously been associated with intelligence and for most of these genes the findings were not reliable.

Taylor and Ehrenreich, however, found that higher - order interactions of five or more places along the genome can have major impacts, and may help explain the so - called «missing heritability» problem, in which additive genetic variants do not entirely explain many inherited diseases and traits.

A high heritability means there is a good chance of increasing this trait in the mink stock.

Twin studies show a higher concordance of AD among monozygotic compared to dizygotic twins, with heritability estimates of 60 % to 80 %.

One possible explanation was that rare variants, which are largely untested by high - density SNP arrays, might account for some of that missing heritability.

In the genomics era, research has focused on the genetic underpinnings of schizophrenia because of the disorder's high heritability.

Generally, traits that are highly inherited (ie largely additively controlled) are not adversely affected by inbreeding but, traits under non-additive control, especially those tied to dominance and thus not of high heritability, are often markedly harmed by inbreeding.

Breed specific behavioural traits such as hunting, herding and calmness / aggression are, however, evidence of a large genetic component and specific behaviours show high heritabilities [4 - 8].

Regardless of the exact mode of inheritance, statistical analysis of this and other studies reveals that LPD has a high degree of heritability.

These results suggest the presence of a major gene, as the heritability was higher than 0.5.

The analyses importantly demonstrated a high degree of heritability, which indicate that, with the correct scheme, eradication of this highly unpleasant condition should be possible within a short time period.

In reality, I think that the heritability of behavioral traits may actually be higher — if you can measure the trait well.

Heritabilities of the majority of traits were higher when the original, more objective neutral descriptors were used.

Chiari - like Malformation (CM) and syringomyelia (SM) is a debilitating and painful disease complex in the Cavalier King Charles Spaniel dog breed (CKCS) which is regarded as a complex oligogenic trait of moderately high heritability [1], [2], [3], [4].

heritability estimates (the percentage of the trait we think is genetically determined) are higher when... more

This study shows that the heritability of clinically diagnosed ADHD is high across the lifespan.

Prepubertal onset has been associated with lower risk of recurrence16, 17; higher risk of bipolar disorder, suicide attempts, alcohol dependence, and conduct disorder17; and lower heritability.18, 19 Results from family studies have been inconsistent.

The results showed that for both childhood and adult antisocial behavior, there was a high degree of heritability involved (Joseph, 2001).

It was hypothesized that divorce would moderate the heritability of DE, in that heritability would be higher in twins from divorced than twins from intact families.

Results: As expected, the heritability of body dissatisfaction was significantly higher in twins from divorced than intact families.

Rather fewer meet the diagnostic criteria for research, which for the oppositional defiant type of conduct disorder seen in younger children require at least four specific behaviours to be present.7 The early onset pattern — typically beginning at the age of 2 or 3 years — is associated with comorbid psychopathology such as hyperactivity and emotional problems, language disorders, neuropsychological deficits such as poor attention and lower IQ, high heritability, 8 and lifelong antisocial behaviour.9 In contrast, teenage onset antisocial behaviour is not associated with other disorders or neuropsychological deficits, is more environmentally determined than inherited, and tends not to persist into adulthood.9

The heritability of borderline personality disorder is estimated to be 0.67 [23], which is similar to or higher than heritability estimates for other major psychiatric disorders.