Sentences with phrase «high levels of risk factors»

The study, the largest of its kind in the world, compared the health of Deaf people with the hearing population and found that Deaf adults have high levels of risk factors for common conditions, such as heart disease, high blood pressure and diabetes.

Not exact matches

Actual results, including with respect to our targets and prospects, could differ materially due to a number of factors, including the risk that we may not obtain sufficient orders to achieve our targeted revenues; price competition in key markets; the risk that we or our channel partners are not able to develop and expand customer bases and accurately anticipate demand from end customers, which can result in increased inventory and reduced orders as we experience wide fluctuations in supply and demand; the risk that our commercial Lighting Products results will continue to suffer if new issues arise regarding issues related to product quality for this business; the risk that we may experience production difficulties that preclude us from shipping sufficient quantities to meet customer orders or that result in higher production costs and lower margins; our ability to lower costs; the risk that our results will suffer if we are unable to balance fluctuations in customer demand and capacity, including bringing on additional capacity on a timely basis to meet customer demand; the risk that longer manufacturing lead times may cause customers to fulfill their orders with a competitor's products instead; the risk that the economic and political uncertainty caused by the proposed tariffs by the United States on Chinese goods, and any corresponding Chinese tariffs in response, may negatively impact demand for our products; product mix; risks associated with the ramp - up of production of our new products, and our entry into new business channels different from those in which we have historically operated; the risk that customers do not maintain their favorable perception of our brand and products, resulting in lower demand for our products; the risk that our products fail to perform or fail to meet customer requirements or expectations, resulting in significant additional costs, including costs associated with warranty returns or the potential recall of our products; ongoing uncertainty in global economic conditions, infrastructure development or customer demand that could negatively affect product demand, collectability of receivables and other related matters as consumers and businesses may defer purchases or payments, or default on payments; risks resulting from the concentration of our business among few customers, including the risk that customers may reduce or cancel orders or fail to honor purchase commitments; the risk that we are not able to enter into acceptable contractual arrangements with the significant customers of the acquired Infineon RF Power business or otherwise not fully realize anticipated benefits of the transaction; the risk that retail customers may alter promotional pricing, increase promotion of a competitor's products over our products or reduce their inventory levels, all of which could negatively affect product demand; the risk that our investments may experience periods of significant stock price volatility causing us to recognize fair value losses on our investment; the risk posed by managing an increasingly complex supply chain that has the ability to supply a sufficient quantity of raw materials, subsystems and finished products with the required specifications and quality; the risk we may be required to record a significant charge to earnings if our goodwill or amortizable assets become impaired; risks relating to confidential information theft or misuse, including through cyber-attacks or cyber intrusion; our ability to complete development and commercialization of products under development, such as our pipeline of Wolfspeed products, improved LED chips, LED components, and LED lighting products risks related to our multi-year warranty periods for LED lighting products; risks associated with acquisitions, divestitures, joint ventures or investments generally; the rapid development of new technology and competing products that may impair demand or render our products obsolete; the potential lack of customer acceptance for our products; risks associated with ongoing litigation; and other factors discussed in our filings with the Securities and Exchange Commission (SEC), including our report on Form 10 - K for the fiscal year ended June 25, 2017, and subsequent reports filed with the SEC.

Factors that could cause actual results to differ include general business and economic conditions and the state of the solar industry; governmental support for the deployment of solar power; future available supplies of high - purity silicon; demand for end - use products by consumers and inventory levels of such products in the supply chain; changes in demand from significant customers; changes in demand from major markets such as Japan, the U.S., India and China; changes in customer order patterns; changes in product mix; capacity utilization; level of competition; pricing pressure and declines in average selling prices; delays in new product introduction; delays in utility - scale project approval process; delays in utility - scale project construction; delays in the completion of project sales; continued success in technological innovations and delivery of products with the features customers demand; shortage in supply of materials or capacity requirements; availability of financing; exchange rate fluctuations; litigation and other risks as described in the Company's SEC filings, including its annual report on Form 20 - F filed on April 27, 2017.

Factors that could cause actual results to differ include general business and economic conditions and the state of the solar industry; governmental support for the deployment of solar power; future available supplies of high - purity silicon; demand for end - use products by consumers and inventory levels of such products in the supply chain; changes in demand from significant customers; changes in demand from major markets such as Japan, the U.S., India and China; changes in customer order patterns; changes in product mix; capacity utilization; level of competition; pricing pressure and declines in average selling prices; delays in new product introduction; delays in utility - scale project approval process; delays in utility - scale project construction; continued success in technological innovations and delivery of products with the features customers demand; shortage in supply of materials or capacity requirements; availability of financing; exchange rate fluctuations; litigation and other risks as described in the Company's SEC filings, including its annual report on Form 20 - F filed on April 20, 2016.

Factors that could cause actual results to differ include general business and economic conditions and the state of the solar industry; governmental support for the deployment of solar power; future available supplies of high - purity silicon; demand for end - use products by consumers and inventory levels of such products in the supply chain; changes in demand from significant customers; changes in demand from major markets such as Japan, the U.S., India and China; changes in customer order patterns; changes in product mix; capacity utilization; level of competition; pricing pressure and declines in average selling prices; delays in new product introduction; delays in utility - scale project approval process; delays in utility - scale project construction; cancelation of utility - scale feed - in - tariff contracts in Japan; continued success in technological innovations and delivery of products with the features customers demand; shortage in supply of materials or capacity requirements; availability of financing; exchange rate fluctuations; litigation and other risks as described in the Company's SEC filings, including its annual report on Form 20 - F filed on April 27, 2017.

Trading foreign exchange on margin carries a high level of risk, as well as its own unique risk factors.

Interest rate risk Although high yield bonds have relatively low levels of interest rate risk for a given duration or maturity compared to other bond types, this risk can nevertheless be a factor.

In the end, it all comes back to education: In the ideal world, a parent's decision about whether to allow a child to start playing or continue playing collision sports before high school under current rules of play (which are evolving in the direction of safety, fortunately, as seen, for instance, in USA Hockey's ban on body checking at the Pee Wee hockey level and below, and limits on full - contact practices instituted at every level of football, from Pop Warner, to high school, college, and the NFL), will be a conscious one; a decision in which the risks of participating in a particular sport - provided it is based on the most up - to - date information about those risks and a consideration of other risk factors that might come into play for their child, such as pre-existing learning disabilities (e.g. ADHD), chronic health conditions (e.g., a history of history of multiple concussions or seizures, history of migraines), or a reckless and overly aggressive style of play - are balanced against the benefits to the child of participating.

More than one third of children eating school lunches already have one of three disease risk factors: high blood pressure, high cholesterol levels or obesity, said Deborah Rees, a dietitian for the Illinois association's nutrition and education training program.

While father absence has been associated with a host of negative children's outcomes, including increased risk of dropping out of school and lower educational attainment, poorer physical and mental health, and behavioural problems,36 - 40 higher levels of involvement by nonresident fathers may assuage the negative effects of father absence on children's outcomes.41, 42 Quality of the parents» relationship before divorce, or of the pre-divorce father / child relationship, can also be an important factor: children fare worse following divorce when pre-divorce relationships were good and fare better when pre-divorce relationships were poor, 43,44 suggesting children are sometimes better off without a father if the father's relationship to the child or the mother was not good.

«Children with low levels of vitamin D were more likely to have high blood pressure and lower levels of high - density lipoprotein, also known as good cholesterol — two factors that are considered major risk factors for heart disease later in life «Children with low vitamin - D levels also had higher levels of parathyroid hormone than their counterparts with adequate vitamin D in their blood.

A bilirubin level of more than 425 μmol / L was chosen to define severe hyperbilirubinemia since an infant with this degree of jaundice is thought to be at high risk of kernicterus.6 Furthermore, the Canadian Paediatric Society recommends considering an exchange transfusion at this level in healthy term infants without risk factors.20

Once researchers adjusted for other factors that could affect dementia risk, such as high blood pressure, high cholesterol and smoking, people with high levels of cynical distrust were three times more likely to develop dementia than people with low levels of cynicism.

Eligible patients presented with tumor stages of T1c to T3a, prostate - specific androgen (PSA) levels of 20 or below, and one or two of three risk factors: stage T3a, a Gleason tumor score of seven or higher, or a PSA level greater than 10.

Metabolic syndrome is a group of risk factors — high blood pressure, high blood sugar, unhealthy cholesterol levels and abdominal fat — that double the risk of blood vessel and heart disease, which can lead to heart attacks and strokes.

This difference was independent of other heart disease risk factors including age, gender, family history, education level, body mass index, smoking habits, hypertension, diabetes and high cholesterol, all of which the researchers adjusted for in their analysis.

In a different study Waghmare presented at the recent annual meeting of the American Society for Blood and Marrow Transplantation in Orlando, Florida, the researchers teased out a few risk factors that can drive the development of lower respiratory tract infections — namely, high levels of steroid use (commonly given to transplant patients for other complications such as graft - vs.

* The ACC / AHA cholesterol treatment guideline recommends prescribing the strongest statins at high doses to most men older than 65, even those with no history of heart disease, or any major risk factor for heart attacks, and with normal cholesterol levels.

high blood pressure levels helped identify lifetime risk of smore accurately in both men and women than any other single risk factor.

Vitamin D deficiency is an independent risk factor for heart disease with lower levels of vitamin D being associated with a higher presence and severity of coronary artery disease, according to research to be presented at the American College of Cardiology's 63rd Annual Scientific Session.

Although cholesterol is a key structural component of cell membranes and is vital for the biosynthesis of certain hormones and vitamins, high levels can lead to the formation of arterial plaques, which are a major risk factor for coronary heart disease.

Higher BMI also increased the overall risk of liver (19 % increase), colon (10 %), ovarian (9 %), and breast cancers (5 %), but the effects on these cancers varied by underlying BMI and by individual - level factors such as sex and menopausal status.

The identification of this and other risk factors (such as lower levels of cognitive stimulation and a higher body mass index) may help us to target individuals for screening, intervention and possible treatment.

In basic analyses reported in the paper, there were several other factors in the study that also predicted a greater likelihood of adopting PrEP: older age, higher perception of HIV risk, sex (either protected or not) with partners outside the main relationship, and having less than a bachelor's degree level of education.

People with high fitness levels in midlife have significantly lower annual health care costs after age 65 than people with low fitness in midlife, after adjusting for cardiovascular risk factors, according to a study published in the Journal of the American College of Cardiology (JACC).

The researchers found that high levels of air pollution, poor quality in the built environment and high levels of sociodemographic risk factors were most strongly associated with increased cancer rates in men and women.

Bovine growth hormone is also known to stimulate the production of insulinlike growth factor 1 (IGF1) by the liver; some studies have shown that high levels of IGF1 in the bloodstream may heighten the risk of prostate and breast cancers as well as a woman's chance of conceiving twins.

As Rand says, «A much higher level of study with more subjects in the cohort would be required before concluding that a genotype [an individual's particular genetic variation] is a risk factor.»

The only known risk factor that is common is a history of high levels of radiation.

«Our findings indicate that sexual minorities living in communities with higher levels of prejudice die sooner than sexual minorities living in low - prejudice communities, and that these effects are independent of established risk factors for mortality, including household income, education, gender, ethnicity, and age, as well as the average income and education level of residents in the communities where the respondents lived,» said Dr. Hatzenbuehler.

In the April 13, 2007, issue of Science, the research team — led by James C. Lo, an MD, PhD student, in the laboratory of Yang - Xin Fu, MD, PhD, professor of pathology at the University of Chicago — suggest that an engineered protein could keep mice, and possibly humans, from developing high cholesterol and triglyceride levels, a key risk factor for coronary heart disease.

African - Americans were also more likely than whites to have traditional risk factors for cardiovascular disease, with significantly higher levels of diabetes, smoking and hypertension.

It has been suggested that a high serum cholesterol level is a risk factor for (AD), and that some polymorphisms of genes encoding proteins regulating cholesterol metabolism are associated with AD development.

Other researchers have identified another factor that could contribute to a correlation between bilingualism and a decreased risk of dementia — the higher education level that is present in some people who speak more than one language.

The researchers also factored in other characteristics of the participants that have previously been correlated with dementia risk including physical activity, age, sex, level of education, obesity, low body mass index (BMI), and a history of high blood pressure, stroke, or diabetes.

A potential explanation for the secular trend may be that while improved treatment for cardiovascular risk factors or complicating diseases has reduced mortality in all weight classes, the effects may have been greater at higher BMI levels than at lower BMI levels.12 Because obesity is a causal risk factor for hypertension, diabetes, cardiovascular disease, and dyslipidemia,15,19 - 22 obese individuals may have had a higher selective decrease in mortality.18 Indirect evidence of this effect is seen in the findings as the deaths occur at similar time periods in the 3 cohorts, but cohorts recruited at later periods have an increase in the BMI associated with the lowest mortality, possibly suggesting a period effect related to changes in clinical practice, such as improved treatments, or general public health status, such as decreased smoking or increased physical activity.

Moreover, risk factors may be different for different individuals - while one person may develop schizophrenia due largely to a strong family history of mental illness (e.g. a high level of genetic risk), someone else with much less genetic vulnerability may also develop the disease due to a more significant combination of prepregnancy factors, pregnancy stress, other prenatal factors, social stress, family stress or environmental factors that they experience during their childhood, teen or early adult years.

People who sleep less may also have higher levels of the stress hormone cortisol, which is a risk factor for heart disease.

Inflammation is a well - known precursor to metabolic syndrome, a group of risk factors — including high blood pressure, high blood sugar, abdominal fat, and unhealthy cholesterol levels — that can trigger obesity and type 2 diabetes.

If the FDA adopts the panel's recommendation — the agency isn't required to do so, but typically does in such cases — it would mark the first time that a statin was approved for heart - disease - free people with healthy cholesterol levels but other risk factors, including high levels of C - reactive protein (CRP), a marker of inflammation.

Take cynicism, for example: A 2014 study published in the journal Neurology linked high levels of cynicism later in life, i.e. a general distrust of people (and their motives), to a greater risk of dementia compared to those who were more trusting, even after accounting for other risk factors like age, sex, certain heart health markers, smoking status, and more.

Bottom line BMI and waist circumference, along with an evaluation of your personal risk factors such as high blood pressure, cholesterol levels, and family history for heart disease, should give you a good idea about whether you need to lose weight.

Pomegranate Keeping a much lower profile than the the goji berry but nutritionally possessing a very good profile indeed, the pomegranate is high in vitamin C, B5 and, most important of all, polyphenols called ellagitannins, which several studies suggest may help to reduce cholesterol levels and other heart disease risk factors.

Researchers have also found that patients with higher BDNF (brain - derived neurotrophic factor) levels have a decreased risk of developing neurodegenerative disorders, such as Alzheimer's and dementia.

It's National Cholesterol Education Month, and clearly, many of us need a refresher: About half of Americans have high or borderline blood cholesterol levels, a major risk factor for heart disease and a serious threat to overall health.

Metabolic syndrome, a cluster of risk factors linked to heart disease and diabetes that includes obesity, high blood sugar, low levels of HDL (good) cholesterol, high triglycerides, and high blood pressure, could also be responsible.

Obesity as well as other risk factors linked to metabolic syndrome are also on the increase in younger people; over 70 % of teenagers in the study had 1 or more of the 5 metabolic syndrome risk factors, namely high blood levels of sugar and fat, high blood pressure, low good cholesterol levels and a large waistline (metabolic syndrome is classified as having 3 or more of the risk factors).

High levels of inflammatory factors increase the risk of cardiovascular diseases and cancer.

One unfortunate down side of a fish heavy diet is that it can be a risk factor for high mercury levels.

Inadequate levels of B6 and B9 in the diet is related to higher homocysteine levels which is an independent risk factor for cardiovascular disease.