Sentences with phrase «high mutation loads»
However, we do encounter negative and positive selection, in addition to genetic drift, at the level of the mutation, usually at high mutation loads.
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We found significantly higher deleterious mutation loads in the genomes of the modern domesticated horses (Fig. 4B), where a higher proportion of sites under strong purifying selection were affected by mutations (SI Appendix, Fig.
Association and prognostic significance of BRCA1 / 2 - mutation status with neoantigen load, number of tumor - infiltrating lymphocytes and expression of PD - 1 / PD - L1 in high grade serous ovarian cancer.