Atherosclerosis is initiated by
high plasma cholesterol leading to monocyte entry into the artery wall and differentiation into macrophages, which take up lipoprotein cholesterol to become lipid engorged foam cells.
Here, we used sequencing - by - ligation to sequence the genome of an 11 - month - old breast - fed girl with xanthomas and very
high plasma cholesterol levels (1023 mg / dl).
On the other hand, breast - fed infants are consistently reported to have
higher plasma cholesterol concentrations than formula - fed infants (22 — 24).
Not exact matches
The idea that
plasma high - density lipoprotein
cholesterol (HDL - C) is protective against coronary heart disease has been part of medical conventional wisdom for five decades.
Researchers at the University of Chicago have found an unsuspected link between the immune system and
high plasma lipid levels (
cholesterol and triglycerides in the blood) in mice.
As expected, animals fed a
high - fat diet had elevated
plasma cholesterol levels (Figure 5D).
When compared with non-carriers, LDLR mutation carriers had
higher plasma LDL
cholesterol, whereas APOA5 mutation carriers had
higher plasma triglycerides.
(D) Fasting
plasma cholesterol levels in mutant mice on a
high - fat diet treated for 5 weeks with control or ApoC - III ASO (n = 5 — 10 / group).
«While the major CVD benefit of statins is due to reduction in
plasma low density lipoprotein
cholesterol (LDL - C), [2] statins also produce moderate increases, ranging from 4 % to 10 %, in levels of
high density lipoprotein
cholesterol (HDL - C).
After consuming a diet with a
high fat content (greater than 100 g fat / day) for two weeks, the mean
plasma cholesterol level increased (p less than 0.02) while the mean SHBG level decreased (p less than 0.02).
Since... infant formulas contain very little
cholesterol (10 to 30 mg / L)(Huisman et al., 1996; Wong et al., 1993), it is not surprising that
plasma cholesterol concentrations are
higher in infants fed human milk than in formula - fed infants.
Dietary glycemic load assessed by food - frequency questionnaire in relation to
plasma high - density - lipoprotein
cholesterol and fasting
plasma triacylglycerols in post-menopausal women
High - monounsaturated fatty acid diets lower both
plasma cholesterol and triacylglycerol concentrations.
Previous studies in normal subjects have reported no effects of the amount of dietary fiber on
plasma triglyceride concentrations.42 In our study, the decrease in
plasma triglyceride and VLDL
cholesterol concentrations during the
high - fiber diet could have been due to the improvement in glycemic control.
As compared with the ADA diet, the
high - fiber diet resulted in a lower fasting
plasma total
cholesterol concentration (by 6.7 percent, P = 0.02), a lower
plasma triglyceride concentration (by 10.2 percent, P = 0.02), and a lower
plasma VLDL
cholesterol concentration (by 12.5 percent, P = 0.01)(Table 4).
The fasting
plasma LDL
cholesterol concentration was 6.3 percent lower with the
high - fiber diet (P = 0.11).
In addition, we studied the effects of such an intervention on the intestinal absorption of
cholesterol and the fecal excretion of sterols in an attempt to uncover the mechanisms by which a
high - fiber diet lowers
plasma cholesterol.
In relation to CVD, elevated blood pressure has been shown to be positively associated with
higher intakes of red and processed meat, even though the mechanism is unclear, except that possibly meat may substitute for other beneficial foods such as grains, fruits, or vegetables.32 Mean
plasma total
cholesterol, low - density lipoprotein
cholesterol, very - low - density lipoprotein
cholesterol, and triglyceride levels were found to be decreased in subjects who substituted red meat with fish.33, 34 Vegetarians have lower arachidonic, eicosapentaenoic, and docosahexaenoic acid levels and
higher linoleate and antioxidant levels in platelet phospholipids; such a biochemical profile may be related to decreased atherogenesis and thrombogenesis.34 - 36
Evidence from some studies48 49 50 51 52 53 54 55 56 has indicated that a
high - carbohydrate diet compared with a
high - unsaturated - fat diet (ie, MUFA), both of which are low in SFA and
cholesterol, can cause an increase in
plasma triglyceride concentrations and a decrease in HDL
cholesterol levels.
Plasma total, LDL, and HDL
cholesterol levels were similar on both diets, although HDL
cholesterol was 4 % lower (P = NS) on the
high - carbohydrate diet.
Freeland - Graves, J. H., Friedman, B. J., Han, W. H., Shorey, R. L., and Young, R. Effect of zinc supplementation on
plasma high - density lipoprotein
cholesterol and zinc.
Low - fat diets do not lower
plasma cholesterol levels in healthy men compared to
high - fat diets with similar fatty acid composition at constant caloric intake