Disproportionately
high plasma insulin concentration in hypertensive patients was first reported in the scientific literature more than fifty years ago.
Not exact matches
Those who ate the diet
higher in fiber had lower levels of both
plasma glucose (blood sugar) and
insulin (the hormone that helps blood sugar get into cells).
Differences in release of
insulin and other pancreatic and gut hormones have also been observed between breastfed and formula - fed infants, with formula feeding leading to
higher plasma levels of
insulin which in turn would stimulate fat deposition and early development of adipocytes, the cells that store fat (18).
However, the CD fed rats gained weight, were
insulin resistant and had
higher plasma lipids than the MCD group (25).
Furthermore, homozygosity for null mutations at CYP2F1 was found associated with
higher plasma interleukin - 8 concentrations; and at either A3GALT2 or NRG4, with markedly reduced
plasma insulin C - peptide concentrations; hence identifying novel phenotypic associations at these genes.
«A
High Fasting
Plasma Insulin Concentration Predicts Type 2 Diabetes Independent of
Insulin Resistance: Evidence for a Pathogenic Role of Relative Hyperinsulinemia,» Diabetes, 49 (12), 2094 - 2101.
Technically diabetes mellitus (DM) is a metabolic disease, where the body is unable to produce enough (or any)
insulin, which causes these very
high glucose levels in blood
plasma of patients who have it.
Patients with advanced AD show
higher plasma but lower CSF
insulin concentrations than healthy controls.40 Clearly, then, the lower concentration of
insulin in the brain is not a result of reduced circulating levels in the blood.
Plasma glucose,
insulin and lipid responses to
high - carbohydrate low - fat diets in normal humans.
You need to have a
high plasma glucose concentration and spiked serum
insulin levels to drive maximum cellular creatine delivery.
Diets
high in protein or saturated fat do not affect
insulin sensitivity or
plasma concentrations of lipids and lipoproteins in overweight and obese adults.
Daily
plasma glucose concentrations were 10 percent lower with the
high - fiber diet than with the ADA diet (values for the area under the curve, 3743 ± 944 vs. 3365 ± 1003 mg ․ hour per deciliter [207.8 ± 52.4 vs. 186.8 ± 55.7 mmol ․ hour per liter]; P = 0.02), and
plasma insulin concentrations were 12 percent lower (values for the area under the curve, 1107 ± 650 vs. 971 ± 491 μU ․ hour per milliliter [6642 ± 3900 vs. 5826 ± 2946 pmol ․ hour per liter]; P = 0.05)(Figure 1).
The
high - fiber diet also lowered the area under the curve for 24 - hour
plasma glucose and
insulin concentrations, which were measured every two hours, by 10 percent (P = 0.02) and 12 percent (P = 0.05), respectively.
Mean (± SE) 24 - Hour Profile of
Plasma Glucose Concentrations (Panel A) and
Insulin Concentrations (Panel B) during the Last Day of the American Diabetes Association (ADA) Diet and the Last Day of the
High - Fiber Diet in 13 Patients with Type 2 Diabetes Mellitus.
Lactate, which increases during starvation, can induce hepatic ketogenesis.2 Low - carbohydrate, fat - rich meals can enhance alpha - cell secretion of glucagon and lower
insulin concentrations.3, 4
Plasma fatty acid concentrations can be twice as
high during low - carbohydrate diets as compared with the usual carbohydrate intake in the postabsorptive period.5 Increased concentrations of free fatty acids in the absence of carbohydrate - induced inhibition of beta - oxidation of fatty acids and in the presence of an abnormally
high ratio of glucagon to
insulin and elevated concentrations of lactate may have caused ketoacidosis in our patient, who was trying to avoid all dietary carbohydrates.