Sentences with phrase «high quality genome»

It must also be clearly stated that sufficient genetic material is available from the study subjects such that a range of sequencing technologies can be used in order to produce high quality genome assemblies.

Ed's lab has recently pioneered a new approach to de novo genome assembly for the company Dovetail Genomics, making high quality genome assemblies faster to produce and affordable for non-model organisms.

While the technology was used with the goal of attaining very high quality genome assemblies, DOE JGI scientists have now additionally taken advantage of this sequencing platform to explore epigenetic (5mC, 6mA) modifications.

«Sequencing technology and computational biology,» Eichler and his team wrote in their paper, «have now advanced to the stage where individual laboratories can generate high quality genomes of mammals.

Not exact matches

Fourth, higher quality maternal interactions have been shown to improve brain development at 5, 10 and 24 months.34 Fifth, there is growing evidence to suggest that the beneficial effects of exclusive breastfeeding may be moderated by the infant's genome, 35,36 and the metabolism of the fatty acids in maternal breast milk.37 For example, Krol et al. 36 showed that infants exclusively breastfed for a longer duration (above the 50th percentile) showed a heightened sensitivity and interest in a happy visual stimulus (eyes) than infants exclusively breastfed for a shorter duration (below the 50th percentile).

By comparing key sites on the tooth DNA with corresponding sites in the high - quality genomes of the Denisova girl, Neandertals, and modern humans, they revealed that the Denisovan inhabitants in that one cave were not closely related.

Jarvis worries that OpenWings will dampen enthusiasm and slow support for B10K, which could cost up to $ 150 million for high quality, so - called reference genomes, and still isn't fully funded.

To obtain the high - quality reference genome needed for this research, the team sequenced a domestic female Abyssinian cat named Cinnamon.

The mouse, dog and human genomes are of high quality whereas the three others are at different stages of analysis completion.»

«For chloroplast genome recovery from total DNA sequence data, the deliberate identification of reads that represent chloroplast DNA inserts into the nuclear genome allowed us to attain a higher - quality chloroplast genome assembly in a time - and cost - effective way,» Garaycochea explains.

In any case, however, high quality nuclear genome data from more than one individual would be necessary to fully investigate this proposed wave of human migration out of Africa, and is an intriguing area for future study.

The first high quality draft of the mouse genome has been greeted by geneticists as a «Rosetta stone» that will help unravel the secrets of our own genes.

«To our knowledge this is the longest genome sequence with the highest quality ever obtained for an extinct avian species,» Hung and his colleagues wrote of the achievement.

Three research groups sequenced high - quality genomes of 787 people from over 270 populations.

This image depicts a phylogenetic tree of over 3,800 high quality and non-redundant bacterial genomes.

The system is designed for projects such as rapid and cost - effective generation of high - quality, whole - genome de novo assemblies.

That's easy: A team of scientists from the United States and France has produced a high - quality draft genome of Coffea canephora.

In the past 6 months, these approaches have led to a flood of high - quality animal and plant genomes in preprints and published papers.

A motivated high school student with access to a nearby biology lab can assemble a reference - quality genome of an actual species, like a butterfly, for the cost of a science fair project.»

However, that DNA was not of high enough quality to enable a complete genome analysis.

If genome sequencing is going to have true medical impact, it needs to get up to [a higher] diagnostic quality level.

The discovery, the product of a multiyear effort to provide a high - quality full genome map of the oil palm plant and to scour the sequence for genes of importance to both science and industry, has major implications for agriculture and the environment.

This will enable the loblolly to serve as a high - quality «reference» genome that considerably speeds along future conifer genome projects.

That genetic explanation was finally made possible because of technology that enabled the lab to perform high - quality sequencing of specific genome regions.

We generated a high - quality draft genome of the species Coffea canephora, which displays a conserved chromosomal gene order among asterid angiosperms.

To create a benchmark for comparison to current database results, the researchers first created the largest, high - quality non-European genome data set ever assembled.

The genome of the Western lowland gorilla has now been sequenced and assembled at a high level of quality beginning to approach that of the mouse and human genome.

«For the first time in animals, we have assembled a high - quality genome, permitting the discovery of all the genetic differences between two individuals within a species,» said Mahul Chakraborty, a postdoctoral scholar in the Emerson laboratory and first author on the study.

All Ion Torrent reads were first aligned against the reference genome using BWA aln (v. 0.7.13)[47] using the default parameters, except for the parameter «- l 1024» to disable the seed and increase high - quality hits for the damaged ancient DNA reads [48].

He is a leader of the recently assembled Simons Genome Diversity Project, which contains 300 high - quality genomes from 142 populations, including the San.

PULLMAN, Wash. — Discovery of the first high - quality genome of quinoa, published this week in Nature, could help create healthier, tastier varieties of this protein - packed «super food.»

The Mouse Genome Sequencing Consortium publishes its efforts of a high - quality sequence and analysis of the mouse gGenome Sequencing Consortium publishes its efforts of a high - quality sequence and analysis of the mouse genomegenome.

To build MIDAS, researchers first generated a database of 31,007 high - quality bacterial genomes.

In collaboration with a group of international colleagues, BTI researchers created a high - quality draft genome sequence of the whitefly and identified genes that code for proteins.

A group of scientists from the United States, Sweden, Canada, and the UK, has sequenced and analyzed the complete high - quality genomes of two woolly mammoths...

This effort is expected to generate a high - quality resource for those responsible for the management of wild salmon stocks and the salmon aquaculture industry, as well as providing a reference genome for work with other salmonids.

Since its introduction a decade ago, whole - genome shotgun sequencing (WGS) has been the main approach for producing cost - effective and high - quality genome sequence data.

An international team of researchers has produced the first high - quality genome sequence for the bottle gourd, also known as calabash, and reconstructed...

Moreover, we demonstrated that although the Oxford Nanopore technology is a relatively new sequencing technology, currently with a high error rate, it is already useful in the generation of high - quality genome assemblies.

A Sanger / pyrosequencing hybrid approach for the generation of high - quality draft assemblies of marine microbial genomes.

High - Quality Draft Genome Sequence of Low - pH - Active Veillonella parvula Strain SHI - 1, Isolated from Human Saliva within an In Vitro Oral Biofilm Model.

We have recently developed hybrid assembly methods that use a combination of short and long reads to produce remarkably high - quality assemblies from whole - genome shotgun data.

The call will enable high quality Swedish research projects to access whole genome sequencing at a greatly reduced cost.

We've made it possible for any researcher to get a high - quality genome assembly for their plant or animal of interest.

Therefore, reducing genome heterozygosity through inbreeding is an effective strategy for acquiring high - quality draft genomes of non-model organisms.

The work consisted of performing whole - genome sequencing on 1,011 samples of yeast which yielded 1,625,809 high - quality reference - based SNPs.

Here we report a high - quality draft genome sequence of the domestic dog (Canis familiaris), together with a dense map of single nucleotide polymorphisms (SNPs) across breeds.

In collaboration with the genome sequencing centres, Vega attempts to present consistent high - quality annotation of the published human chromosome sequences.

Short Research Paper High Quality Draft Genomes of the Type Strains Geobacillus thermocatenulatus DSM 730T, G. uzenensis DSM 23175T And Parageobacillus galactosidasius DSM 18751T Winnie Thabisa Ramaloko, Nadine Koen, Shamara Polliack, Habibu Aliyu, Pedro Humberto Lebre, Teresa Mohr, Florian Oswald, Michaela Zwick, Daniel Ray Zeigler, Anke Neumann, Christoph Syldatk, Don Arthur Cowan, Pieter De Maayer J. Genomics 2018; 6: 20 - 23.

The new high - quality PcyM assembly has an improved representation of the subtelomeric regions of the genome, which now encompass nearly 40 % of the genome sequence.